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癌症患者血清对体外T淋巴细胞行为的修饰作用

T-lymphocyte behaviour modification in vitro by cancer patient sera.

作者信息

Santamaría M, García-Espejo R, Molina I, Ortega M C, Pera C, Peña J

出版信息

Rev Esp Fisiol. 1985 Jun;41(2):221-3.

PMID:3875882
Abstract

Cell mediated immune response blocking factor(s) in the serum of colon adenocarcinoma patients inhibit blast transformation of lymphocytes from normal individuals. The blocking capacity of the sera has been shown to correlate with the infiltration of the tumor. This correlation suggests that these phenomena may be mediated by identical serum factors and through a common cell receptor present in the lymphocytes of normal individuals.

摘要

结肠癌患者血清中的细胞介导免疫反应阻断因子可抑制正常个体淋巴细胞的母细胞转化。已证明血清的阻断能力与肿瘤浸润相关。这种相关性表明,这些现象可能由相同的血清因子介导,并通过正常个体淋巴细胞中存在的共同细胞受体介导。

相似文献

1
T-lymphocyte behaviour modification in vitro by cancer patient sera.癌症患者血清对体外T淋巴细胞行为的修饰作用
Rev Esp Fisiol. 1985 Jun;41(2):221-3.
2
Adenosine suppresses alpha(4)beta(7) integrin-mediated adhesion of T lymphocytes to colon adenocarcinoma cells.腺苷抑制α(4)β(7)整合素介导的T淋巴细胞与结肠腺癌细胞的黏附。
Exp Cell Res. 2002 May 15;276(1):90-100. doi: 10.1006/excr.2002.5514.
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Correlation between serum alpha-globulin and plasma inhibitory effect on PHA-stimulated lymphocytes in colon cancer patients.结肠癌患者血清α球蛋白与血浆对PHA刺激淋巴细胞的抑制作用之间的相关性。
Proc Soc Exp Biol Med. 1972 Feb;139(2):575-8. doi: 10.3181/00379727-139-36189.
4
Effect of sera of patients with genitourinary tract cancers on transformation of lymphocytes stimulated with anti-thymocyte globulin.泌尿生殖道癌症患者血清对用抗胸腺细胞球蛋白刺激的淋巴细胞转化的影响。
Natl Cancer Inst Monogr. 1978 Dec(49):127-30.
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Scanning electron microscopy of interaction of peripheral blood lymphocytes from colonic cancer patients with human colonic cancer-derived cells; P-4788.结肠癌患者外周血淋巴细胞与人结肠癌衍生细胞(P-4788)相互作用的扫描电子显微镜观察
Acta Med Okayama. 1979 Dec;33(6):431-42.
6
The effects of uremic serum and 3'-5' cyclic AMP on blastogenesis of normal lymphocytes.尿毒症血清及3',5'-环磷酸腺苷对正常淋巴细胞增殖的影响。
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Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of t-cell function in advanced cancer patients.活化的粒细胞和粒细胞衍生的过氧化氢是晚期癌症患者T细胞功能受抑制的潜在机制。
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[Effect of anti-inflammatory drugs on transformation of human T-lymphocytes to blast-like cells induced by PHA and on one-way mixed lymphocyte reaction].
Eisei Shikenjo Hokoku. 1984(102):36-9.
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[Effect of antibiotics on human lymphocyte mitogenesis].[抗生素对人淋巴细胞有丝分裂的影响]
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Haematological correlates of phytohaemagglutinin-induced lymphocyte transformation in horses.马体内植物血凝素诱导淋巴细胞转化的血液学相关性
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