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Serum exosomal tsRNA biomarkers: A novel strategy for identifying lupus nephritis.

作者信息

Yang Ping, Sun Yifan, Wang Chenlan, Li Zhibo, Han Yiyuan, Gong Jianming, Khan Adeel, Wang Jin, Wang Yanbo, Jin Fangfang, Li Zhiyang

机构信息

Department of Clinical Laboratory, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.

State Key Laboratory of Pharmaceutical Biotechnology, Department of Physiology, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, School of Life Sciences, NJU Advanced Institute of Life Sciences, Nanjing University, Nanjing, China.

出版信息

Clin Transl Med. 2024 May;14(5):e1677. doi: 10.1002/ctm2.1677.

DOI:10.1002/ctm2.1677
PMID:38760892
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11101668/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa9/11101668/40d43c28f4f7/CTM2-14-e1677-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa9/11101668/a176a47b4542/CTM2-14-e1677-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa9/11101668/52da42c05695/CTM2-14-e1677-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa9/11101668/40d43c28f4f7/CTM2-14-e1677-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa9/11101668/a176a47b4542/CTM2-14-e1677-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa9/11101668/52da42c05695/CTM2-14-e1677-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa9/11101668/40d43c28f4f7/CTM2-14-e1677-g001.jpg

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本文引用的文献

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Extracellular Vesicles as an Endocrine Mechanism Connecting Distant Cells.细胞外囊泡作为一种连接远隔细胞的内分泌机制。
Mol Cells. 2022 Nov 30;45(11):771-780. doi: 10.14348/molcells.2022.0110. Epub 2022 Nov 3.
2
Serum tsRNA as a novel molecular diagnostic biomarker for lupus nephritis.血清tsRNA作为狼疮性肾炎的新型分子诊断生物标志物。
Clin Transl Med. 2022 May;12(5):e830. doi: 10.1002/ctm2.830.
3
A Novel Serum tsRNA for Diagnosis and Prediction of Nephritis in SLE.一种新型血清 tsRNA 用于 SLE 肾炎的诊断和预测。
转运RNA衍生片段：自身免疫性疾病中的生物标志物与治疗靶点
Immunol Res. 2025 May 22;73(1):85. doi: 10.1007/s12026-025-09639-0.
4
Comprehensive profiling of tsRNAs in acute coronary syndrome: expression patterns, clinical correlations, and functional insights.急性冠状动脉综合征中tsRNA的综合分析：表达模式、临床相关性及功能见解
Hum Genet. 2025 May;144(5):575-590. doi: 10.1007/s00439-025-02742-0. Epub 2025 Apr 15.
5
Machine Learning-Based Identification of Novel Exosome-Derived Metabolic Biomarkers for the Diagnosis of Systemic Lupus Erythematosus and Differentiation of Renal Involvement.基于机器学习识别新型外泌体衍生代谢生物标志物用于系统性红斑狼疮的诊断及肾脏受累的鉴别
Curr Med Sci. 2025 Apr;45(2):231-243. doi: 10.1007/s11596-025-00023-5. Epub 2025 Feb 28.
6
tRNA-derived small RNAs: their role in the mechanisms, biomarkers, and therapeutic strategies of colorectal cancer.转运RNA衍生的小RNA：它们在结直肠癌的机制、生物标志物及治疗策略中的作用
J Transl Med. 2025 Jan 13;23(1):51. doi: 10.1186/s12967-025-06109-x.
7
and : key renal biomarkers in lupus nephritis.以及：狼疮肾炎的关键肾脏生物标志物。
PeerJ. 2024 Sep 16;12:e18070. doi: 10.7717/peerj.18070. eCollection 2024.
Front Immunol. 2021 Nov 11;12:735105. doi: 10.3389/fimmu.2021.735105. eCollection 2021.
4
A novel class of tsRNA signatures as biomarkers for diagnosis and prognosis of pancreatic cancer.一类新型的tsRNA特征作为胰腺癌诊断和预后的生物标志物。
Mol Cancer. 2021 Jul 17;20(1):95. doi: 10.1186/s12943-021-01389-5.
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PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications.PANDORA-seq 通过克服 RNA 修饰来扩展调控性小 RNA 的 repertoire。
Nat Cell Biol. 2021 Apr;23(4):424-436. doi: 10.1038/s41556-021-00652-7. Epub 2021 Apr 5.
6
Update οn the diagnosis and management of systemic lupus erythematosus.红斑狼疮诊断与治疗的最新进展。
Ann Rheum Dis. 2021 Jan;80(1):14-25. doi: 10.1136/annrheumdis-2020-218272. Epub 2020 Oct 13.
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2019 Update of the Joint European League Against Rheumatism and European Renal Association-European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of lupus nephritis.2019 年更新版欧洲抗风湿病联盟与欧洲肾脏学会-欧洲透析和移植学会（EULAR/ERA-EDTA）狼疮肾炎管理建议。
Ann Rheum Dis. 2020 Jun;79(6):713-723. doi: 10.1136/annrheumdis-2020-216924. Epub 2020 Mar 27.
8
Lupus nephritis.狼疮性肾炎。
Nat Rev Dis Primers. 2020 Jan 23;6(1):7. doi: 10.1038/s41572-019-0141-9.
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Vitamin D and systemic lupus erythematosus - The hype and the hope.维生素 D 与系统性红斑狼疮——炒作与希望。
Autoimmun Rev. 2018 Jan;17(1):19-23. doi: 10.1016/j.autrev.2017.11.004. Epub 2017 Nov 3.
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Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus.更新美国风湿病学会系统性红斑狼疮分类的修订标准。
Arthritis Rheum. 1997 Sep;40(9):1725. doi: 10.1002/art.1780400928.