Tribology Group, Department of Mechanical Engineering, Faculty of Engineering, Imperial College London, South Kensington Campus, London SW7 2AZ, UK.
Tribology Group, Department of Mechanical Engineering, Faculty of Engineering, Imperial College London, South Kensington Campus, London SW7 2AZ, UK.
J Mech Behav Biomed Mater. 2024 Jul;155:106574. doi: 10.1016/j.jmbbm.2024.106574. Epub 2024 May 14.
A full understanding of the material properties of skin tissue is crucial for exploring its tribo-mechanical behaviour. It has been widely accepted that the mechanical behaviour of skin tissue for both small and large deformations can be accurately described using a hyperelastic model, such as the one developed by Ogden. However, obtaining these Ogden parameters for in-vivo skin by in-vivo experiments no matter the indentation or suction tests is a significant challenge. The mathematical model used to describe the material behaviour during the test should consider not only the material nonlinearity but also the geometrical confinement of the tissue, the large deformations induced, and the fact that the specimens are relatively thin. A range of contact models is available to describe the contact behaviour during the indentation test. However, none of them can be used for hyperelastic materials with small thickness under large deformations. Simultaneously explaining material nonlinearity and geometric nonlinearity, either through theoretical equations or numerical calculations, poses a significant challenge. In this research, we propose a pragmatic method to obtain Ogden parameters for in-vivo skin tissue by combining experimental indentation results and numerical simulations. The indentation tests were used to obtain the force-indentation depth curves, while the numerical simulations were used to obtain the strain fields. The method assumes the material behaviour of specimens can be linearized in each small deformation increment, and the contact model developed by Hayes can be applied to accommodate each increment. Then, the linear elastic behaviour in each increment can be described by the elastic modulus E which were obtained using Hayes model, and the principal stresses in each increment were subsequently obtained using Hooke's law. By combining all stress fields, overall stress-strain curves can be constructed, from which the hyperelastic Ogden parameters can be obtained. A second numerical simulation of the hyperelastic indentation was then performed using the obtained Ogden parameters, allowing a comparison of the experimental and simulated relationships between force and indentation.
全面了解皮肤组织的材料特性对于探索其摩擦力学行为至关重要。人们普遍认为,无论是小变形还是大变形,皮肤组织的力学行为都可以通过超弹性模型(如 Ogden 模型)准确描述。然而,无论采用压痕还是抽吸试验,通过体内实验获得体内皮肤的这些 Ogden 参数都是一个重大挑战。用于描述测试期间材料行为的数学模型不仅应考虑材料非线性,还应考虑组织的几何约束、诱导的大变形以及标本相对较薄的事实。有一系列接触模型可用于描述压痕试验期间的接触行为。然而,在大变形下,对于小厚度的超弹性材料,没有一种模型可以使用。同时通过理论方程或数值计算来解释材料非线性和几何非线性,这是一个重大挑战。在这项研究中,我们提出了一种实用的方法,通过结合实验压痕结果和数值模拟来获得体内皮肤组织的 Ogden 参数。压痕试验用于获得力-压痕深度曲线,而数值模拟用于获得应变场。该方法假设在每个小变形增量中,试样的材料行为可以线性化,并且可以应用 Hayes 开发的接触模型来适应每个增量。然后,可以使用 Hayes 模型获得的弹性模量 E 来描述每个增量中的线性弹性行为,并且可以随后使用胡克定律获得每个增量中的主应力。通过组合所有的应力场,可以构建整体的应力-应变曲线,从中可以获得超弹性的 Ogden 参数。然后使用获得的 Ogden 参数对超弹性压痕进行第二次数值模拟,从而可以比较实验和模拟的力与压痕之间的关系。