Fulbright R K, Wolf J E, Tschen J A
J Dermatol Surg Oncol. 1985 Sep;11(9):883-6. doi: 10.1111/j.1524-4725.1985.tb03559.x.
Pyoderma gangrenosum is a necrotizing and ulcerative skin disorder often associated with underlying systemic diseases. The etiology remains obscure, with recent investigations emphasizing an altered immune system. A case report is presented of pyoderma gangrenosum occurring at surgical sites in the absence of predisposing factors. Pyoderma gangrenosum in this setting can mimic infectious causes of wound necrosis. Early recognition of the characteristic lesion morphology may prevent unnecessary treatment directed toward infectious agents and facilitate effective control with systemic corticosteroid therapy.
坏疽性脓皮病是一种坏死性和溃疡性皮肤疾病,常与潜在的全身性疾病相关。其病因仍不清楚,近期研究强调免疫系统发生了改变。本文报告了一例在无诱发因素情况下发生于手术部位的坏疽性脓皮病。这种情况下的坏疽性脓皮病可能会模仿伤口坏死的感染性病因。早期识别特征性病变形态可避免针对感染病原体进行不必要的治疗,并有助于通过全身皮质类固醇治疗实现有效控制。