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使用注射用富血小板纤维蛋白阻止瘢痕性脱发的进展

Halting the Progression of Cicatricial Alopecia with Injectable Platelet-Rich Fibrin.

作者信息

Chikhalkar Siddhi Bhalchandra, Singh Surender, Shah Avani Jatin Kumar, Madke Bhushan, Kabbannavar Yallappa Ramchandrappa

机构信息

Department of Dermatology, Seth G. S. Medical College and K. E. M Hospital, Mumbai, Maharashtra, India.

Department of Dermatology, Venereology and Leprosy, Jawahalal Nehru Medical College, Datta Meghe Institute of Medical Science, Wardha, Maharashtra, India.

出版信息

Int J Trichology. 2023 Jul-Aug;15(4):163-166. doi: 10.4103/ijt.ijt_116_21. Epub 2024 Apr 5.

Abstract

Discoid lupus erythematosus (DLE) is a chronic variant of cutaneous lupus erythematosus characterized by well-defined erythematous plaques with adherent scales and follicular plugging. The affected scalp shows erythema, edema, atrophy, alopecia, and telangiectasia. Trichoscopy of DLE shows branching capillaries, white patches, keratin plugs, reduced follicular ostia, and white dots and blue-gray dots arranged in speckles pattern. Prompt diagnosis and aggressive, early multimodal therapy helps in preventing disfiguring hair loss and psychosocial sequelae. Hereby, we present a case of reversal of hair loss in DLE with newer modalities of treatment such as injectable platelet-rich fibrin.

摘要

盘状红斑狼疮(DLE)是皮肤红斑狼疮的一种慢性变体,其特征为边界清晰的红斑斑块,伴有黏附鳞屑和毛囊堵塞。受累头皮表现为红斑、水肿、萎缩、脱发和毛细血管扩张。DLE的皮肤镜检查显示分支状毛细血管、白色斑块、角质栓、毛囊口减少,以及呈斑点状排列的白色小点和蓝灰色小点。及时诊断并积极进行早期多模式治疗有助于预防毁容性脱发和心理社会后遗症。在此,我们报告一例通过注射富血小板纤维蛋白等新型治疗方法使DLE脱发得到逆转的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ac6/11098144/dfceee7f640b/IJT-15-163-g001.jpg

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