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波索尔犬群体中原发性进行性家族性甲状腺炎的临床和组织学特征

Clinical and histological features of primary progressive, familial thyroiditis in a colony of borzoi dogs.

作者信息

Conaway D H, Padgett G A, Bunton T E, Nachreiner R, Hauptman J

出版信息

Vet Pathol. 1985 Sep;22(5):439-46. doi: 10.1177/030098588502200502.

DOI:10.1177/030098588502200502
PMID:3876642
Abstract

A six-year study of clinical data and the morphologic changes involved in lymphocytic thyroiditis in a colony of related borzoi dogs was conducted. Lesions observed included initial degenerative thyroidal parenchymal changes which progressed to subacute inflammation with subsequent fibrosis and end stage thyroid gland disease. This study encompasses three successive generations of this borzoi colony and documents the progression of the histologic changes from the initial thyroid gland degenerative lesions to the end stage parenchymal atrophy. Spontaneous, familial thyroiditis has not been reported previously in the borzoi breed.

摘要

对一群相关的波索尔犬进行了一项为期六年的研究,该研究涉及淋巴细胞性甲状腺炎的临床数据和形态学变化。观察到的病变包括甲状腺实质的初始退行性变化,这些变化进展为亚急性炎症,随后出现纤维化和终末期甲状腺疾病。这项研究涵盖了该波索尔犬群的三代犬,并记录了组织学变化从最初的甲状腺退行性病变到终末期实质萎缩的进展过程。此前尚未有关于波索尔犬品种自发性、家族性甲状腺炎的报道。

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