Office of the Associate Director, Behavioral Research Program, National Cancer Institute, Bethesda, MD, USA.
Health Communication and Informatics Research Branch, Behavioral Research Program, National Cancer Institute, Bethesda, MD, USA.
Am J Mens Health. 2024 May-Jun;18(3):15579883241252524. doi: 10.1177/15579883241252524.
Awareness of risk for oropharyngeal cancer from oral human papillomavirus (HPV) infection is low among men in the United States. This pilot study tested messages communicating oral HPV and oropharyngeal cancer risk among a sample of U.S. young adult men (aged 18-26). Six oral HPV and cancer risk messages were tested in an online survey. Participants ( = 68) were randomly assigned to one of two message sets, each containing three unique text-based messages. Participants evaluated messages separately based on various measures (e.g., perceived message effectiveness [PME], novelty). One-way repeated measures ANOVAs were used to assess evaluation differences within message sets. Participants provided open-ended feedback about each message, which were synthesized into overarching themes. Participants were receptive to the risk messages, rating them high on PME (mean range = 3.72-4.25 out of 5) and other measures. Analyses identified three high-performing messages. For example, participants rated a message about HPV-linked oropharyngeal cancer risk rates in men versus women higher on attention and novelty than two other messages in the same set (both s < .05). Participants were shown three messages (instead of all six) in each message set to minimize survey fatigue. Common themes from open-ended feedback were that participants liked the short-form structure of the messages and that the messages used gender-tailored language. In conclusion, oral HPV and oropharyngeal cancer risk messages may be useful for increasing risk awareness among men in the U.S. Further work should test such messages in rigorous experimental contexts to assess their efficacy in modifying other health outcomes, such as HPV vaccination behaviors.
美国男性对口咽癌源自人乳头瘤病毒（HPV）感染的风险意识较低。本试点研究检验了针对美国年轻成年男性（18-26 岁）的口腔 HPV 和口咽癌风险信息的传播效果。在一项在线调查中，测试了六种口腔 HPV 和癌症风险信息。参与者（n=68）被随机分配到两个信息组中的一个，每个信息组包含三条独特的基于文本的信息。参与者根据各种衡量标准（例如，感知信息有效性 [PME]、新颖性）分别对信息进行评估。采用单因素重复测量方差分析来评估信息组内的评估差异。参与者就每条信息提供了开放性反馈，这些反馈被综合成总体主题。参与者对风险信息持接受态度，对 PME（5 分制中均值范围为 3.72-4.25）和其他衡量标准的评分较高。分析确定了三条表现较好的信息。例如，与同一信息组中的另外两条信息相比，参与者认为一条关于 HPV 相关口咽癌男性与女性风险率的信息在关注度和新颖性方面得分更高（均 s<0.05）。在每个信息组中，向参与者展示了三条信息（而不是全部六条），以尽量减少调查疲劳。开放性反馈中的常见主题是，参与者喜欢信息的短格式结构，并且信息使用了性别定制语言。总之，口腔 HPV 和口咽癌风险信息可能有助于提高美国男性的风险意识。进一步的研究应在严格的实验环境中测试此类信息，以评估其在改变其他健康结果（如 HPV 疫苗接种行为）方面的效果。
