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马拉松运动员血压过度升高与心血管重构。

Excessive Blood Pressure Rise and Cardiovascular Remodeling in Marathon Runners.

机构信息

Division of Cardiology, Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea (the Republic of).

Department of exercise rehabilitation & Welfare, Sungshin Women's University, Seongbuk-gu, Korea (the Republic of).

出版信息

Int J Sports Med. 2024 Oct;45(12):930-936. doi: 10.1055/a-2330-9869. Epub 2024 May 21.

DOI:10.1055/a-2330-9869
PMID:38772403
Abstract

Exercise-induced hypertension (EIH) is thought to be associated with increased cardiovascular (CV) risks. However, no previous studies have investigated the effects of EIH on CV systems in marathon runners without CV risk factors using both 24-hr ambulatory blood pressure (BP) monitoring and exercise stress echocardiography (ESE). This study firstly described differences in CV adaptations according to EIH assessed by both exams. Marathon runners between 35 and 64 years of age without CV risk factors were eligible. All the participants underwent both 24-hr ambulatory BP monitoring and ESE. EIH was defined as a maximal exercise systolic BP≥210 mmHg. The EIH group (n=19) had shorter training history and higher exercise intensity compared to the non-EIH group (n=23). The average systolic BP was higher in the EIH group than in the non-EIH group. Left cardiac chamber size and left ventricular mass (LVM) were also higher in the EIH group compared to the non-EIH group. Maximal BP during ESE was positively correlated with both parameters. Exaggerated BP response during exercise needs to be monitored for pre-emptive measurements before it results in progressive cardiovascular maladaptation.

摘要

运动诱导性高血压(EIH)被认为与心血管(CV)风险增加有关。然而,以前的研究没有使用 24 小时动态血压监测和运动超声心动图(ESE)调查无 CV 危险因素的马拉松运动员的 EIH 对 CV 系统的影响。本研究首先描述了通过这两种检查评估的 EIH 差异对 CV 适应的影响。年龄在 35 至 64 岁之间且无 CV 危险因素的马拉松运动员符合条件。所有参与者都接受了 24 小时动态血压监测和 ESE。EIH 定义为最大运动收缩压≥210mmHg。与非 EIH 组(n=23)相比,EIH 组(n=19)的训练历史更短,运动强度更高。EIH 组的平均收缩压高于非 EIH 组。EIH 组的左心腔大小和左心室质量(LVM)也高于非 EIH 组。ESE 期间的最大血压与这两个参数呈正相关。运动期间血压反应过度需要进行监测,以便在其导致进行性心血管适应不良之前进行预防性测量。

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J Clin Med. 2025 Jun 23;14(13):4466. doi: 10.3390/jcm14134466.