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在非允许温度下阻断蛋白质合成对大肠杆菌温度敏感型脱氧核糖核酸突变体的影响。

Effect of blocking protein synthesis at nonpermissive temperatures on temperature-sensitive deoxyribonucleic acid mutants of Escherichia coli.

作者信息

Evans I M, Forrest N, Lawrence A, Eberle H

出版信息

J Bacteriol. 1979 Nov;140(2):445-51. doi: 10.1128/jb.140.2.445-451.1979.

DOI:10.1128/jb.140.2.445-451.1979
PMID:387736
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC216668/
Abstract

When protein synthesis was blocked in temperature-sensitive deoxyribonucleic acid synthesis mutants of Escherichia coli at nonpermissive temperatures, it reduced the amount of apparent subsequent chain elongation to approximately half that observed in the mutants either at nonpermissive temperatures alone or when protein synthesis was blocked at the permissive temperature. Blocking protein synthesis at the nonpermissive temperatures for periods of 40 min caused the loss of ability to reinitiate deoxyribonucleic acid synthesis at the permissive temperature.

摘要

当在非允许温度下阻断大肠杆菌温度敏感型脱氧核糖核酸合成突变体中的蛋白质合成时,它会将明显的后续链延伸量减少至在单独处于非允许温度下的突变体中或在允许温度下阻断蛋白质合成时所观察到的量的大约一半。在非允许温度下阻断蛋白质合成40分钟会导致在允许温度下重新启动脱氧核糖核酸合成的能力丧失。

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Effect of blocking protein synthesis at nonpermissive temperatures on temperature-sensitive deoxyribonucleic acid mutants of Escherichia coli.在非允许温度下阻断蛋白质合成对大肠杆菌温度敏感型脱氧核糖核酸突变体的影响。
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本文引用的文献

1
THE EFFECT OF AMINO ACID DEPRIVATION ON SUBSEQUENT DEOXYRIBONUCLEIC ACID REPLICATION.氨基酸剥夺对后续脱氧核糖核酸复制的影响。
Biochim Biophys Acta. 1963 Sep 17;76:9-24.
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Thymine deficiency and the normal DNA replication cycle. I.胸腺嘧啶缺乏与正常DNA复制周期。I.
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Regulation of chromosome replication and segregation in bacteria.细菌中染色体复制与分离的调控
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4
Escherichia coli mutants temperature-sensitive for DNA synthesis.对DNA合成温度敏感的大肠杆菌突变体。
Mol Gen Genet. 1971;113(3):273-84. doi: 10.1007/BF00339547.
5
Chromosome replication in Escherichia coli K12 mutant affected in the process of DNA initiation.在DNA起始过程中受到影响的大肠杆菌K12突变体中的染色体复制。
Genetics. 1971 Sep;69(1):1-15. doi: 10.1093/genetics/69.1.1.
6
Temperature-sensitive initiation of DNA replication in a mutant of Escherichia coli K12.大肠杆菌K12突变体中DNA复制的温度敏感起始
Mol Gen Genet. 1971;111(2):145-58. doi: 10.1007/BF00267789.
7
Escherichia coli mutants with temperature-sensitive synthesis of DNA.具有温度敏感型DNA合成能力的大肠杆菌突变体。
Mol Gen Genet. 1970;109(2):107-22. doi: 10.1007/BF00269647.
8
On the process of cellular division in Escherichia coli. Membrane prtein alterations associated with mutations affecting the initiation of DNA synthesis.关于大肠杆菌细胞分裂过程。与影响DNA合成起始的突变相关的膜蛋白改变。
J Mol Biol. 1970 Aug 28;52(1):75-89. doi: 10.1016/0022-2836(70)90178-6.
9
Analysis of the chloramphenicol-sensitive and chloramphenicol-resistant steps in the initiation of DNA synthesis in E. coli B-r.大肠杆菌B-r中DNA合成起始过程中氯霉素敏感和耐药步骤的分析。
Proc Natl Acad Sci U S A. 1969 Nov;64(3):905-12. doi: 10.1073/pnas.64.3.905.
10
Temperature-sensitive initiation of chromosome replication in a mutant of Escherichia coli.大肠杆菌突变体中染色体复制的温度敏感起始
J Bacteriol. 1969 Dec;100(3):1302-10. doi: 10.1128/jb.100.3.1302-1310.1969.