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通过差示傅里叶变换红外光谱对原肽缩合进行定性监测

Qualitative Monitoring of Proto-Peptide Condensation by Differential FTIR Spectroscopy.

作者信息

Rezaeerod Keon, Heinzmann Hanna, Torrence Alexis V, Patel Jui, Forsythe Jay G

机构信息

Department of Chemistry and Biochemistry, College of Charleston, Charleston, South Carolina 29424, United States.

Analytical and Bioanalytical Chemistry, Aalen University, 73430 Aalen, Germany.

出版信息

ACS Earth Space Chem. 2024 May 6;8(5):937-944. doi: 10.1021/acsearthspacechem.3c00257. eCollection 2024 May 16.

DOI:10.1021/acsearthspacechem.3c00257
PMID:38774359
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11103710/
Abstract

Condensation processes such as wet-dry cycling are thought to have played significant roles in the emergence of proto-peptides. Here, we describe a simple and low-cost method, differential Fourier transform infrared (FTIR) spectroscopy, for qualitative analysis of peptide condensation products in model primordial reactions. We optimize differential FTIR for depsipeptides and apply this method to investigate their polymerization in the presence of extraterrestrial dust simulants.

摘要

诸如干湿循环这样的缩合过程被认为在原始肽的出现过程中发挥了重要作用。在此，我们描述了一种简单且低成本的方法——差分傅里叶变换红外（FTIR）光谱法，用于对模拟原始反应中的肽缩合产物进行定性分析。我们针对环肽优化了差分FTIR，并应用该方法研究它们在外星尘埃模拟物存在下的聚合反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69db/11103710/d9faa82a5053/sp3c00257_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69db/11103710/40839a1f4aaf/sp3c00257_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69db/11103710/658cc9c0aef4/sp3c00257_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69db/11103710/eee333de3d27/sp3c00257_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69db/11103710/8fa965c67454/sp3c00257_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69db/11103710/d9faa82a5053/sp3c00257_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69db/11103710/40839a1f4aaf/sp3c00257_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69db/11103710/658cc9c0aef4/sp3c00257_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69db/11103710/eee333de3d27/sp3c00257_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69db/11103710/8fa965c67454/sp3c00257_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69db/11103710/d9faa82a5053/sp3c00257_0005.jpg

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