Department of Clinical Pharmacy and Practice, Faculty of Pharmacy and Medical Sciences, Hebron University, Hebron, West Bank, Palestine.
J Int Med Res. 2024 May;52(5):3000605241248041. doi: 10.1177/03000605241248041.
To investigate factors related to the risk of developing irritable bowel syndrome (IBS) or infection.
This cross-sectional, questionnaire-based study analysed the responses from participants that completed an online questionnaire, which asked about their knowledge of the causes and risk factors associated with IBS and infection.
The study analysed responses from 230 participants: 181 females (of 227 participants; 79.7%) and 190 aged 18-40 years (of 228; 83.3%). Of the 230 participants, 40 (17.4%) had been diagnosed by a physician with IBS and 57 (24.8%) had been diagnosed with infection. Of 226 participants, 93 (41.2%) had self-medicated with antibiotics in the past 6 months for various reasons. The overall mean ± SD knowledge score about IBS and infection for the study cohort ( = 230) was 35.8 ± 19.2%. Wald χ-test analysis demonstrated that chronic diseases, antibiotic use and having an endoscopy were significantly associated with developing IBS. Male sex and chronic diseases were significantly associated with infection. Logistic regression analysis showed no relationship between IBS and infection.
Chronic diseases was the only risk factor common for IBS and infection.
研究与肠易激综合征（IBS）或感染相关的风险因素。
本横断面问卷调查研究分析了完成在线问卷的参与者的回答，该问卷询问了他们对 IBS 和感染相关病因和风险因素的了解。
本研究分析了 230 名参与者的回答：181 名女性（227 名参与者中；79.7%）和 190 名年龄在 18-40 岁（228 名中；83.3%）。230 名参与者中，40 名（17.4%）被医生诊断为 IBS，57 名（24.8%）被诊断为感染。在 226 名参与者中，93 名（41.2%）因各种原因在过去 6 个月内自行使用抗生素进行治疗。总体而言，研究队列（n=230）对 IBS 和感染的平均知识得分（ = 230）为 35.8 ± 19.2%。Wald χ检验分析表明，慢性疾病、抗生素使用和内镜检查与 IBS 的发生显著相关。男性和慢性疾病与感染显著相关。逻辑回归分析显示 IBS 和感染之间没有关系。
慢性疾病是 IBS 和感染的唯一共同危险因素。
