无症状个体中酒精、吸烟和感染之间的关系存在性别差异。
Sex differences in the relationship among alcohol, smoking, and infection in asymptomatic individuals.
机构信息
Department of Gastroenterology and Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Institute of Clinical and Preventive Medicine, University of Latvia; Digestive Diseases Centre Gastro, Riga, Latvia.
出版信息
J Int Med Res. 2020 May;48(5):300060520926036. doi: 10.1177/0300060520926036.
OBJECTIVE
We aimed to investigate the relationship of infection with alcohol and smoking.
METHODS
We conducted a cross-sectional study among participants who underwent health check-ups for infection between January 2013 and March 2017. We subsequently investigated the relationship of infection with alcohol and smoking.
RESULTS
A total of 7169 participants were enrolled in this study. The overall prevalence of infection was 55.2%. Participants with infection were more likely to be older than those without infection. For male participants with infection, multivariable logistic regression analysis indicated that both smoking (odds ratio (OR): 1.61; 95% confidence interval (CI): 1.41-1.83) and alcohol consumption (OR: 1.30; 95% CI: 1.10-1.52) were independently positively associated with infection. For female participants, multivariable logistic regression analysis indicated that both smoking (OR: 0.03; 95% CI: 0.02-0.07) and alcohol consumption (OR: 0.20; 95% CI: 0.12-0.33) were inversely significantly associated with infection after adjustment for age.
CONCLUSIONS
Smoking and alcohol consumption were risk factors for male participants but these were protective factors for female individuals with infection.
目的
本研究旨在探讨感染与饮酒和吸烟之间的关系。
方法
我们对 2013 年 1 月至 2017 年 3 月间进行健康检查的感染参与者进行了横断面研究。随后，我们调查了感染与饮酒和吸烟之间的关系。
结果
共有 7169 名参与者纳入本研究。感染的总患病率为 55.2%。感染患者比未感染患者年龄更大。对于感染的男性参与者，多变量逻辑回归分析表明，吸烟（比值比（OR）：1.61；95%置信区间（CI）：1.41-1.83）和饮酒（OR：1.30；95% CI：1.10-1.52）均与感染独立正相关。对于感染的女性参与者，多变量逻辑回归分析表明，吸烟（OR：0.03；95% CI：0.02-0.07）和饮酒（OR：0.20；95% CI：0.12-0.33）在调整年龄后与感染呈负相关。
结论
吸烟和饮酒是男性参与者感染的危险因素，但对于女性感染者来说，这些因素是保护因素。
Zotero 插件