Halkai Kiran R, Halkai Rahul
Department of Conservative Dentistry and Endodontics, Al-Badar Rural Dental College and Hospital, Kalaburgi, Karnataka, India.
J Conserv Dent Endod. 2024 Apr;27(4):414-418. doi: 10.4103/JCDE.JCDE_36_24. Epub 2024 Apr 5.
Coronavirus disease 2019 (COVID-19) has vastly affected mankind worldwide, and its long-term effect on oral health needs to be studied.
The aim of the study was to evaluate the prevalence of dental caries and its correlation with salivary total antioxidant capacity (TAC) in Kalaburagi region of the Indian subpopulation.
About 80 subjects (16-55 years) were included in the study based on selection criteria and were divided into two groups ( = 40). Group 1: no history of COVID-19 infection and Group 2: COVID-19-recovered subjects. Each group was subdivided into two subgroups ( = 20) A and B with and without dental caries. Dental caries was assessed using the decay, missing, filled, treatment (DMFT) index by the World Health Organization. About 5 ml of unstimulated saliva samples was collected and centrifuged at 2000 rpm for 10 min, and the supernatants were collected. Salivary TAC was estimated using 2,2'-azino-bis-[3-ethylbenzothiazoline-6-sulfonic] acid assay and observed under spectrophotometer (734 nm).
Data were analyzed using the Shapiro-Wilk test for normality distribution followed by one-way analysis of variance and post hoc Tukey test ( < 0.05).
COVID-19-recovered subjects showed a higher prevalence of dental caries and lower TAC levels than non-COVID-19 subjects.
Higher prevalence of dental caries with lower levels of salivary TAC was found in COVID-19-recovered individuals.
2019年冠状病毒病（COVID-19）已在全球范围内对人类产生了巨大影响，其对口腔健康的长期影响有待研究。
本研究旨在评估印度亚人群卡拉布尔吉地区龋齿的患病率及其与唾液总抗氧化能力（TAC）的相关性。
根据选择标准，约80名受试者（16 - 55岁）被纳入研究，并分为两组（每组n = 40）。第1组：无COVID-19感染史；第2组：COVID-19康复者。每组再细分为有和无龋齿的两个亚组（每组n = 20）A和B。使用世界卫生组织的龋失补治疗（DMFT）指数评估龋齿情况。收集约5毫升未刺激的唾液样本，以2000转/分钟的速度离心10分钟，收集上清液。使用2,2'-联氮-双-（3-乙基苯并噻唑啉-6-磺酸）酸法测定唾液TAC，并在分光光度计（734纳米）下观察。
数据采用Shapiro-Wilk检验进行正态分布分析，随后进行单因素方差分析和事后Tukey检验（P < 0.05）。
COVID-19康复者的龋齿患病率高于非COVID-19受试者，且TAC水平较低。
在COVID-19康复个体中发现龋齿患病率较高且唾液TAC水平较低。
