P Swarna Meenakshi, Rajasekar Arvina
Periodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Cureus. 2024 Apr 22;16(4):e58792. doi: 10.7759/cureus.58792. eCollection 2024 Apr.
Background and objective The objective of this study is to evaluate and compare the surrogate and true end points following surgical periodontal therapy using the Oral Health Impact Profile-14 (OHIP-14) questionnaire. Materials and methods The study included a total of 30 participants, comprising 15 males and 15 females aged between 25 and 50 years. All individuals who had undergone periodontal flap surgery for generalized chronic periodontitis at the Department of Periodontology, Saveetha Dental College and Hospitals were included in the study. The OHIP-14 questionnaire was used to assess the patient-centered outcomes (true end points) pre- and post-flap surgery at baseline and six months. Surrogate end points such as the clinical attachment level (CAL), probing pocket depth (PPD), and gingival index (GI) were recorded at baseline and six months pre- and post-flap surgery. Results Clinical parameters such as the GI (p=0.03*), CAL (p=0.03), and PPD (p=0.02*) showed a statistically significant improvement after surgery. Patient-centered outcomes showed statistically significant differences in terms of taste perception, reduction in pain sensation, improvement in self-consciousness and reduction in anxiety levels, diminution of the feeling of embarrassment and enhancement in the ability to relax due to problems associated with gums, and improvement in the workplace (p<0.05) post-operatively. Conclusion Surgical periodontal therapy plays a pivotal role in improving oral health-related quality of life (OHRQoL) among patients with chronic periodontal disease. Utilizing OHIP-14 as an assessment tool enables a comprehensive evaluation of treatment outcomes, encompassing various dimensions of oral health impact. Patient-centered outcomes such as psychological discomfort and functional limitations can be achieved only by an interdisciplinary approach.
背景与目的 本研究的目的是使用口腔健康影响程度量表-14(OHIP-14)问卷评估和比较牙周手术治疗后的替代终点和真实终点。材料与方法 本研究共纳入30名参与者,包括15名男性和15名女性,年龄在25至50岁之间。所有在萨维塔牙科学院及医院牙周科接受过广泛性慢性牙周炎牙周翻瓣手术的个体均纳入本研究。OHIP-14问卷用于在基线和六个月时评估翻瓣手术前后以患者为中心的结局(真实终点)。在基线以及翻瓣手术前后六个月记录替代终点,如临床附着水平(CAL)、探诊深度(PPD)和牙龈指数(GI)。结果 术后GI(p=0.03*)、CAL(p=0.03)和PPD(p=0.02*)等临床参数显示出统计学上的显著改善。以患者为中心的结局在味觉感知、疼痛感觉减轻、自我意识改善、焦虑水平降低、因牙龈问题导致的尴尬感减轻以及放松能力增强和工作场所改善方面术后有统计学显著差异(p<0.05)。结论 牙周手术治疗在改善慢性牙周病患者的口腔健康相关生活质量(OHRQoL)方面起着关键作用。使用OHIP-14作为评估工具能够全面评估治疗结局,涵盖口腔健康影响的各个维度。只有通过多学科方法才能实现以患者为中心的结局,如心理不适和功能限制。