Lafong A C
Ulster Med J. 1985 Apr;54(1):58-60.
Fourteen out of 150 (9.3%) consecutive strains of Haemophilus influenzae isolated on culture of sputum in the Bacteriology Department, Belfast City Hospital, during 1982/83 were found to be ampicillin-resistant (beta-lactamase-producing). Susceptibility testing to other antibiotics of these ampicillin-resistant strains showed that cefuroxime, cefotaxime, gentamicin, and amoxycillin with clavulanic acid were reliable alternatives. Other useful alternatives included tetracycline, trimethoprim and co-trimoxazole. Erythromycin was of limited usefulness.
1982/83年期间,在贝尔法斯特市医院细菌学部门对痰液进行培养时分离出的150株流感嗜血杆菌连续菌株中,有14株(9.3%)被发现对氨苄西林耐药(产β-内酰胺酶)。对这些耐氨苄西林菌株进行的其他抗生素敏感性测试表明,头孢呋辛、头孢噻肟、庆大霉素以及阿莫西林与克拉维酸是可靠的替代药物。其他有用的替代药物包括四环素、甲氧苄啶和复方新诺明。红霉素的作用有限。