Bull World Health Organ. 1985;63(4):661-6.
The important challenge of prevention and control of rabies in the world will require international efforts to increase the availability and use of high quality cell-culture rabies vaccines for use in man and animals. An important aspect of activities to ensure such availability is transfer of technologies to developing countries for production of these vaccines. This article, which is based on the report of a WHO Consultation, outlines the technical options for vaccine production. The principles and economic aspects of technology transfer are considered, and a WHO assistance programme is outlined. It is concluded that technology transfer should be mediated through a framework of national institutes, expert panels, WHO collaborating centres, production and control laboratories, and other relevant institutions. On this basis, recommendations are made concerning the mechanisms of technology transfer for production of cell-culture rabies vaccines.
全球狂犬病防控面临的一项重大挑战是，需要通过国际合作，提高优质细胞培养狂犬病疫苗的可及性，并促进其在人和动物中的使用。确保此类疫苗可及性的活动的一个重要方面是，向发展中国家转让生产这些疫苗的技术。本文基于世界卫生组织一次磋商会的报告，概述了疫苗生产的技术选择，探讨了技术转让的原则和经济因素，并概述了世卫组织的援助计划。得出的结论是，技术转让应通过国家机构、专家小组、世卫组织合作中心、生产与控制实验室以及其他相关机构组成的框架进行协调。在此基础上，就细胞培养狂犬病疫苗生产的技术转让机制提出了建议。
