• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

埃及癫痫管理共识指南:一项全国德尔菲共识研究。

Consensus Guideline on the Management of Epilepsy in Egypt: A National Delphi Consensus Study.

机构信息

Neurology Department, Faculty of Medicine, Cairo University, Giza, Egypt.

Neurology Department, Faculty of Medicine, Assiut University, Asyut, Egypt.

出版信息

Epilepsia Open. 2024 Aug;9(4):1233-1251. doi: 10.1002/epi4.12922. Epub 2024 May 24.

DOI:10.1002/epi4.12922
PMID:38790148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11296093/
Abstract

OBJECTIVE

In epilepsy, early diagnosis, accurate determination of epilepsy type, proper selection of antiseizure medication, and monitoring are all essential. However, despite recent therapeutic advances and conceptual reconsiderations in the classification and management of epilepsy, serious gaps are still encountered in day-to-day practice in Egypt as well as several other resource-limited countries. Premature mortality, poor quality of life, socio-economic burden, cognitive problems, poor treatment outcomes, and comorbidities are major challenges that require urgent actions to be implemented at all levels. In recognition of this, a group of Egyptian epilepsy experts met through a series of consecutive meetings to specify the main concepts concerning the diagnosis and management of epilepsy, with the ultimate goal of establishing a nationwide Egyptian consensus.

METHODS

The consensus was developed through a modified Delphi methodology. A thorough review of the most recent relevant literature and international guidelines was performed to evaluate their applicability to the Egyptian situation. Afterward, several remote and live rounds were scheduled to reach a final agreement for all listed statements.

RESULTS

Of 278 statements reviewed in the first round, 256 achieved ≥80% agreement. Live discussion and refinement of the 22 statements that did not reach consensus during the first round took place, followed by final live voting then consensus was achieved for all remaining statements.

SIGNIFICANCE

With the implementation of these unified recommendations, we believe this will bring about substantial improvements in both the quality of care and treatment outcomes for persons with epilepsy in Egypt.

PLAIN LANGUAGE SUMMARY

This work represents the efforts of a group of medical experts to reach an agreement on the best medical practice related to people with epilepsy based on previously published recommendations while taking into consideration applicable options in resource-limited countries. The publication of this document is expected to minimize many malpractice issues and pave the way for better healthcare services on both individual and governmental levels.

摘要

目的

在癫痫中,早期诊断、准确确定癫痫类型、适当选择抗癫痫药物以及监测都至关重要。然而,尽管最近在癫痫的治疗进展和分类管理方面有了概念上的重新考虑,但在埃及以及其他一些资源有限的国家,日常实践中仍然存在严重的差距。过早死亡、生活质量差、社会经济负担、认知问题、治疗效果不佳和合并症都是需要在各个层面立即采取行动的主要挑战。认识到这一点,一组埃及癫痫专家通过一系列连续会议会面,明确了有关癫痫诊断和管理的主要概念,最终目标是在全国范围内建立埃及共识。

方法

通过修改后的 Delphi 方法制定共识。对最新的相关文献和国际指南进行了全面审查,以评估其对埃及情况的适用性。之后,安排了几次远程和现场会议,以就所有列出的陈述达成最终协议。

结果

在第一轮中审查的 278 条陈述中,有 256 条达到了≥80%的一致性。对第一轮中未达成共识的 22 条陈述进行了现场讨论和细化,随后进行了最终现场投票,所有其余陈述均达成共识。

意义

实施这些统一的建议,我们相信这将为埃及的癫痫患者带来护理质量和治疗效果的显著改善。

通俗易懂的摘要

这是一组医学专家的努力,旨在根据以前发表的建议,同时考虑资源有限国家的适用方案,就与癫痫患者相关的最佳医疗实践达成一致。该文件的发布有望最大限度地减少许多医疗事故问题,并为个人和政府层面的更好医疗服务铺平道路。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e4b/11296093/6d8417acc391/EPI4-9-1233-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e4b/11296093/b169f8026567/EPI4-9-1233-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e4b/11296093/e8e0621c7903/EPI4-9-1233-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e4b/11296093/6d8417acc391/EPI4-9-1233-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e4b/11296093/b169f8026567/EPI4-9-1233-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e4b/11296093/e8e0621c7903/EPI4-9-1233-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e4b/11296093/6d8417acc391/EPI4-9-1233-g003.jpg

相似文献

1
Consensus Guideline on the Management of Epilepsy in Egypt: A National Delphi Consensus Study.埃及癫痫管理共识指南:一项全国德尔菲共识研究。
Epilepsia Open. 2024 Aug;9(4):1233-1251. doi: 10.1002/epi4.12922. Epub 2024 May 24.
2
Methodology for the development of National Multidisciplinary Management Recommendations using a multi-stage meta-consensus initiative.采用多阶段元共识倡议制定国家多学科管理建议的方法。
BMC Med Res Methodol. 2022 Jul 11;22(1):189. doi: 10.1186/s12874-022-01667-w.
3
Management goals of type 1 Gaucher disease in South Africa: An expert Delphi consensus document on good clinical practice.南非 1 型戈谢病的管理目标:关于良好临床实践的专家德尔菲共识文件。
PLoS One. 2023 Aug 22;18(8):e0290401. doi: 10.1371/journal.pone.0290401. eCollection 2023.
4
International Delphi Consensus on the Management of AQP4-IgG+ NMOSD: Recommendations for Eculizumab, Inebilizumab, and Satralizumab.国际 AQP4-IgG+ NMOSD 管理德尔菲共识:依库珠单抗、埃替珠单抗和 satralizumab 的推荐意见。
Neurol Neuroimmunol Neuroinflamm. 2023 May 31;10(4). doi: 10.1212/NXI.0000000000200124. Print 2023 Jul.
5
A T2 Translational Science Modified Delphi Study: Spinal Motion Restriction in a Resource-Scarce Environment.一项T2转化科学改良德尔菲研究:资源匮乏环境下的脊柱活动限制
Prehosp Disaster Med. 2020 Oct;35(5):538-545. doi: 10.1017/S1049023X20000862. Epub 2020 Jul 9.
6
The International Liaison Committee on Resuscitation (ILCOR) consensus on science with treatment recommendations for pediatric and neonatal patients: pediatric basic and advanced life support.国际复苏联合委员会(ILCOR)关于儿科和新生儿患者的科学共识及治疗建议:儿科基础与高级生命支持
Pediatrics. 2006 May;117(5):e955-77. doi: 10.1542/peds.2006-0206. Epub 2006 Apr 17.
7
Consensus-based guidelines for Video EEG monitoring in the pre-surgical evaluation of children with epilepsy in the UK.英国癫痫患儿术前评估中视频脑电图监测的基于共识的指南。
Seizure. 2017 Aug;50:6-11. doi: 10.1016/j.seizure.2017.05.008. Epub 2017 May 12.
8
The future of Cochrane Neonatal.考克兰新生儿协作网的未来。
Early Hum Dev. 2020 Nov;150:105191. doi: 10.1016/j.earlhumdev.2020.105191. Epub 2020 Sep 12.
9
Use of Bone Marrow Concentrate to Treat Pain and Musculoskeletal Disorders: An Academic Delphi Investigation.使用骨髓浓缩物治疗疼痛和肌肉骨骼疾病:一项学术德尔菲调查。
Pain Physician. 2021 May;24(3):263-273.
10
EPICON consensus: recommendations for proper management of switching to eslicarbazepine acetate in epilepsy.EPICON共识:癫痫患者转换为醋酸艾司利卡西平恰当管理的建议
Neurologia (Engl Ed). 2018 Jun;33(5):290-300. doi: 10.1016/j.nrl.2016.04.014. Epub 2016 Jun 24.

引用本文的文献

1
The impact of nursing intervention on the care burden experienced by mothers of children with epilepsy: a family-centered empowerment model.护理干预对癫痫患儿母亲护理负担的影响:一种以家庭为中心的赋权模式。
BMC Nurs. 2025 Jul 9;24(1):894. doi: 10.1186/s12912-025-03532-9.

本文引用的文献

1
Roles of fMRI and Wada tests in the presurgical evaluation of language functions in temporal lobe epilepsy.功能磁共振成像(fMRI)和Wada测试在颞叶癫痫语言功能术前评估中的作用。
Front Neurol. 2022 Sep 30;13:884730. doi: 10.3389/fneur.2022.884730. eCollection 2022.
2
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.抗癫痫药物单药治疗癫痫:一项个体参与者数据的网络荟萃分析。
Cochrane Database Syst Rev. 2022 Apr 1;4(4):CD011412. doi: 10.1002/14651858.CD011412.pub4.
3
Prevalence, incidence, and risk factors of epilepsy in arab countries: A systematic review.
阿拉伯国家癫痫的患病率、发病率和危险因素:系统评价。
Seizure. 2021 Nov;92:40-50. doi: 10.1016/j.seizure.2021.07.031. Epub 2021 Aug 1.
4
The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial.SANAD II 研究:丙戊酸钠与左乙拉西坦治疗新诊断的全面性和不可分类癫痫的有效性和成本效益:一项开放标签、非劣效性、多中心、4 期、随机对照试验。
Lancet. 2021 Apr 10;397(10282):1375-1386. doi: 10.1016/S0140-6736(21)00246-4.
5
The SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide, or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial.SANAD II 研究:左乙拉西坦、唑尼沙胺或拉莫三嗪治疗新诊断局灶性癫痫的有效性和成本效益:一项开放标签、非劣效性、多中心、4 期、随机对照试验。
Lancet. 2021 Apr 10;397(10282):1363-1374. doi: 10.1016/S0140-6736(21)00247-6.
6
Treatment strategies for encephalopathy related to status epilepticus during slow sleep, a narrative review of the literature.慢波睡眠相关癫痫持续状态性脑病的治疗策略:文献综述。
Rev Neurosci. 2020 Oct 25;31(7):793-802. doi: 10.1515/revneuro-2020-0020.
7
Febrile infection-related epilepsy syndrome (FIRES): prevalence, impact and management strategies.发热感染相关癫痫综合征(FIRES):患病率、影响及管理策略
Neuropsychiatr Dis Treat. 2019 Jul 9;15:1897-1903. doi: 10.2147/NDT.S177803. eCollection 2019.
8
Recommendations for the use of structural magnetic resonance imaging in the care of patients with epilepsy: A consensus report from the International League Against Epilepsy Neuroimaging Task Force.推荐使用结构磁共振成像技术于癫痫患者的临床诊疗:国际抗癫痫联盟神经影像学工作组的共识报告。
Epilepsia. 2019 Jun;60(6):1054-1068. doi: 10.1111/epi.15612. Epub 2019 May 28.
9
Global, regional, and national burden of epilepsy, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.全球、区域和国家癫痫负担,1990-2016 年:2016 年全球疾病负担研究的系统分析。
Lancet Neurol. 2019 Apr;18(4):357-375. doi: 10.1016/S1474-4422(18)30454-X. Epub 2019 Feb 14.
10
Prevalence of childhood and adolescence epilepsy in Upper Egypt (desert areas).上埃及(沙漠地区)儿童及青少年癫痫的患病率
Egypt J Neurol Psychiatr Neurosurg. 2018;54(1):34. doi: 10.1186/s41983-018-0032-0. Epub 2018 Nov 9.