Kotova T S, German G P, Chernokhvostova E V
Vopr Med Khim. 1985 Nov-Dec;31(6):46-50.
Ability of monoclonal immunoglobulins (IgG, IgA, IgM and IgD) to develop complexes with albumin and alpha 1-proteinase inhibitor (alpha 1-PI) was studied using methods of immunoelectrophoresis, cross immunoelectrophoresis and immunoselection. High of proteins, producing complexes with albumin, was found among monoclonal IgA, IgM and IgG; alpha 1-PI formed complexes mainly with IgA and IgM. In healthy volunteers complexes of blood serum proteins were not found. Albumin and alpha 1-PI developed complexes most often with various molecules of monoclonal immunoglobulins. Ability to produce complexes did not depend on the type of the paraprotein.
运用免疫电泳、交叉免疫电泳和免疫选择法研究了单克隆免疫球蛋白（IgG、IgA、IgM和IgD）与白蛋白及α1-蛋白酶抑制剂（α1-PI）形成复合物的能力。在单克隆IgA、IgM和IgG中发现有与白蛋白形成复合物的高蛋白；α1-PI主要与IgA和IgM形成复合物。在健康志愿者中未发现血清蛋白复合物。白蛋白和α1-PI最常与各种单克隆免疫球蛋白分子形成复合物。形成复合物的能力不取决于副蛋白的类型。
