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军事任务中的氧化应激——影响与管理策略:一项叙述性分析

Oxidative Stress in Military Missions-Impact and Management Strategies: A Narrative Analysis.

作者信息

Radulescu Dumitru, Mihai Florina-Diana, Trasca Major Emil-Tiberius, Caluianu Elena-Irina, Calafeteanu Captain Dan Marian, Radulescu Patricia-Mihaela, Mercut Razvan, Ciupeanu-Calugaru Eleonora Daniela, Marinescu Georgiana-Andreea, Siloşi Cristian-Adrian, Nistor Colonel Claudiu Eduard, Danoiu Suzana

机构信息

Department of Surgery, The Military Emergency Clinical Hospital 'Dr. Stefan Odobleja' Craiova, 200749 Craiova, Romania.

Doctoral School, University of Medicine and Pharmacy of Craiova, 2 Petru Rares Street, 200349 Craiova, Romania.

出版信息

Life (Basel). 2024 Apr 27;14(5):567. doi: 10.3390/life14050567.

DOI:10.3390/life14050567
PMID:38792589
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11121804/
Abstract

This narrative review comprehensively examines the impact of oxidative stress on military personnel, highlighting the crucial role of physical exercise and tailored diets, particularly the ketogenic diet, in minimizing this stress. Through a meticulous analysis of the recent literature, the study emphasizes how regular physical exercise not only enhances cardiovascular, cognitive, and musculoskeletal health but is also essential in neutralizing the effects of oxidative stress, thereby improving endurance and performance during long-term missions. Furthermore, the implementation of the ketogenic diet provides an efficient and consistent energy source through ketone bodies, tailored to the specific energy requirements of military activities, and significantly contributes to the reduction in reactive oxygen species production, thus protecting against cellular deterioration under extreme stress. The study also underlines the importance of integrating advanced technologies, such as wearable devices and smart sensors that allow for the precise and real-time monitoring of oxidative stress and physiological responses, thus facilitating the customization of training and nutritional regimes. Observations from this review emphasize significant variability among individuals in responses to oxidative stress, highlighting the need for a personalized approach in formulating intervention strategies. It is crucial to develop and implement well-monitored, personalized supplementation protocols to ensure that each member of the military personnel receives a regimen tailored to their specific needs, thereby maximizing the effectiveness of measures to combat oxidative stress. This analysis makes a valuable contribution to the specialized literature, proposing a detailed framework for addressing oxidative stress in the armed forces and opening new directions for future research with the aim of optimizing clinical practices and improving the health and performance of military personnel under stress and specific challenges of the military field.

摘要

本叙述性综述全面考察了氧化应激对军事人员的影响,强调了体育锻炼和定制饮食,特别是生酮饮食,在最小化这种应激方面的关键作用。通过对近期文献的细致分析,该研究强调定期体育锻炼不仅能增强心血管、认知和肌肉骨骼健康,而且对于抵消氧化应激的影响至关重要,从而提高长期任务期间的耐力和表现。此外,生酮饮食的实施通过酮体提供了一种高效且持续的能量来源,适合军事活动的特定能量需求,并显著有助于减少活性氧的产生,从而防止在极端应激下细胞退化。该研究还强调了整合先进技术的重要性,如可穿戴设备和智能传感器,它们能够精确实时监测氧化应激和生理反应,从而便于定制训练和营养方案。本综述的观察结果强调个体对氧化应激的反应存在显著差异,突出了在制定干预策略时采用个性化方法的必要性。制定和实施经过良好监测的个性化补充方案至关重要,以确保军事人员中的每一个成员都能获得适合其特定需求的方案,从而最大限度地提高对抗氧化应激措施的有效性。这一分析对专业文献做出了宝贵贡献,提出了一个应对武装部队氧化应激的详细框架,并为未来研究开辟了新方向,旨在优化临床实践,改善军事人员在应激和军事领域特定挑战下的健康和表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bf6/11121804/8434f1f0e7af/life-14-00567-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bf6/11121804/8434f1f0e7af/life-14-00567-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bf6/11121804/8434f1f0e7af/life-14-00567-g001.jpg

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