Institute for Pulmonary Rehabilitation Research, Schoen Klinik Berchtesgadener Land, 83471 Schoenau am Koenigssee, Germany.
Department of Medicine V, Comprehensive Pneumology Center Munich (CPC-M), German Center for Lung Research (DZL), Ludwig-Maximilians University (LMU) University Hospital, 81377 Munich, Germany.
Viruses. 2024 Apr 29;16(5):709. doi: 10.3390/v16050709.
Due to immunosuppression, transplant recipients are at higher risk of infections with SARS-CoV-2 and worse clinical outcomes than immunocompetent hosts. Furthermore, lung transplant patients represent a special group among solid organ recipients, since pneumonia is the main manifestation of COVID-19. However, data on the course of disease and the changes in morbidity and mortality during the course of the pandemic are limited. In our pulmonary rehabilitation clinic, we treat patients shortly after lung transplant as well as long-term transplant patients. Over the last almost 4 years of pandemic, we witnessed several COVID-19 infections in lung transplant patients in our clinic as well as patients who acquired an infection beforehand. In this paper, we aim at retrospectively describing a series of recent COVID-19 cases in our clinic, looking at the clinical course of disease and outcomes in lung transplant patients.
由于免疫抑制，移植受者感染 SARS-CoV-2 的风险更高，临床结局比免疫功能正常的宿主更差。此外，肺移植患者是实体器官受者中的一个特殊群体，因为肺炎是 COVID-19 的主要表现。然而，关于疾病过程以及大流行期间发病率和死亡率变化的数据有限。在我们的肺康复诊所，我们治疗肺移植后不久的患者以及长期移植患者。在过去近 4 年的大流行期间，我们在诊所看到了几例肺移植患者感染 COVID-19，以及之前感染过的患者。在本文中，我们旨在回顾性描述我们诊所最近的一系列 COVID-19 病例，观察肺移植患者的疾病临床过程和结局。
