Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Russia.
Dokl Biochem Biophys. 2024 Jun;516(1):107-110. doi: 10.1134/S1607672924700807. Epub 2024 May 25.
The dynamics of the pulse wave (PW) associated with the PW transit time variability (PWTTV) determines the peripheral pulse rate variability, which is used as a surrogate for heart rate variability (HRV). The aim of the work is to analyze the frequency-dependent dynamics of PWTTV and to identify the possible frequency-phase modulation of PW velocity oscillations on the transit from the heart to the soft tissues of the distal parts of the upper extremities. RR-interval recordings and synchronous records of photoplethysmograms of 12 conditionally healthy subjects from the PhysioNet open database were used in this work. Using the Hilbert-Huang transform 3 spectral components of PWTTV and HRV were identified. It was shown that the amplitudes of PWTTV oscillations were many times (up to 8.4 times) smaller than the amplitudes of HRV, and the peaks of PWTTV spectral components were shifted towards higher frequencies than those of HRV. Functional relations between PWTTV and HRV, which can determine the phase modulation of periodic changes in the PW propagation velocity, were revealed.
脉搏波（PW）的动力学及其传输时间变异性（PWTTV）决定了周围脉搏率变异性，可作为心率变异性（HRV）的替代指标。本研究旨在分析 PWTTV 的频率依赖性动力学，并确定 PW 速度振荡从心脏传输到上肢远端软组织时可能存在的频率-相位调制。RR 间期记录和来自 PhysioNet 开放数据库的 12 名条件健康受试者的光体积描记图的同步记录用于本工作。使用希尔伯特-黄变换，确定了 PWTTV 和 HRV 的 3 个谱分量。结果表明，PWTTV 振荡的幅度比 HRV 的幅度小很多倍（高达 8.4 倍），并且 PWTTV 谱分量的峰值比 HRV 的峰值向更高的频率移动。揭示了 PWTTV 和 HRV 之间的功能关系，这可以确定 PW 传播速度周期性变化的相位调制。
