Department of Psychology, University of Alabama at Birmingham, United States.
Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, 1720 2nd Ave S, SC 1004, Birmingham, AL 35294, United States.
Seizure. 2024 Jul;119:58-62. doi: 10.1016/j.seizure.2024.05.009. Epub 2024 May 16.
The present study sought to assess the effects of racial and socioeconomic status in the United States on time to treatment and diagnosis of pediatric functional seizures (FS).
Eighty adolescents and their parent/guardian completed a demographics questionnaire and reported date of FS onset, diagnosis, and treatment. Paired samples t-tests compared time between FS onset and diagnosis, onset and treatment, and diagnosis and treatment based on race (White vs racial minority), annual household income (≤$79,999 vs ≥$80,000), maternal and paternal education (≤Associate's Degree vs Bachelor's Degree), and combined parental education (≤Post-graduate training vs Graduate degree).
Adolescents with lower annual household income began treatment >6 months later than adolescents with greater annual household income (p = 0.049). Adolescents with lower maternal and paternal education (≤Associate's Degree vs Bachelor's Degree) began treatment >4 and ∼8.5 months later than adolescents with greater maternal and paternal education (p = 0.04; p = 0.03), respectively. Adolescents with lower maternal education also received a diagnosis >5 months later (p = 0.03). Adolescents without a mother or father with a graduate degree received a diagnosis and began treatment∼3 and >11 months later (p = 0.03; p = 0.01) than adolescents whose mother or father received a graduate degree, respectively. No racial differences were found.
Adolescents with lower annual household income and/or parental education experienced increased duration between FS onset and treatment and diagnosis. Research is needed to clarify the mechanisms underlying this relationship, and action is needed to reduce these disparities given FS duration is associated with poorer prognosis and greater effects on the brain.
本研究旨在评估美国的种族和社会经济地位对儿科功能性癫痫(FS)的治疗和诊断时间的影响。
80 名青少年及其父母/监护人完成了一份人口统计学问卷,并报告了 FS 发病、诊断和治疗的日期。配对样本 t 检验比较了 FS 发病与诊断、发病与治疗、诊断与治疗之间的时间,根据种族(白人与少数民族)、家庭年收入(≤79999 美元与≥80000 美元)、母亲和父亲的教育程度(≤副学士学位与学士学位)以及父母的综合教育程度(≤研究生培训与研究生学位)进行比较。
家庭年收入较低的青少年开始治疗的时间比家庭年收入较高的青少年晚了>6 个月(p = 0.049)。母亲和父亲的教育程度较低(≤副学士学位与学士学位)的青少年开始治疗的时间比母亲和父亲的教育程度较高的青少年晚了>4 个月和8.5 个月(p = 0.04;p = 0.03)。母亲教育程度较低的青少年的诊断时间也晚了>5 个月(p = 0.03)。没有母亲或父亲拥有研究生学位的青少年的诊断和治疗开始时间分别比母亲或父亲拥有研究生学位的青少年晚了3 个月和>11 个月(p = 0.03;p = 0.01)。没有发现种族差异。
家庭年收入和/或父母教育程度较低的青少年在 FS 发病与治疗和诊断之间的时间间隔较长。需要进一步研究来阐明这种关系的机制,并采取行动来减少这些差异,因为 FS 的持续时间与预后较差和对大脑的影响更大有关。