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意大利老年人综合老年评估指南:25 个意大利科学学会和国家卫生研究所的合作成果。

The Italian guideline on comprehensive geriatric assessment (CGA) for the older persons: a collaborative work of 25 Italian Scientific Societies and the National Institute of Health.

机构信息

Department of Geriatric Care, Neurology and Rehabilitation, Galliera Hospitals, Genoa, Italy.

Department of Interdisciplinary Medicine, "Aldo Moro" University of Bari, Bari, Italy.

出版信息

Aging Clin Exp Res. 2024 May 27;36(1):121. doi: 10.1007/s40520-024-02772-0.

Abstract

BACKGROUND

The guideline was promoted by the Italian General Practitioners-Primary Care and Geriatrics Hospital-Community Societies and was carried out involving the National Institute of Health and an Expert Panel including representatives from 25 Scientific and Health-Professional Organizations. The aim of the Guideline was to develop evidence-based recommendations on the efficacy of CGA in older people across different clinical settings and the accuracy and utility of CGA-based tools to assess prognosis.

METHODS

According to the methodological handbook of the Italian National System of Guidelines and NICE criteria (National Institute for Health and Care Excellence in England), the Guideline was produced based on the Grading of Recommendations Assessment, Development and Evaluation. Over 20,000 records gathered through databases searches were initially selected. Sixteen recommendations on CGA efficacy were defined based on 117 studies that met the inclusion criteria and were performed in general practices and primary care (26 studies included), medical and surgical clinics (16 studies), emergency departments (17 studies), hospital medical and surgical wards (53 studies), long-term care facilities and nursing homes (5 studies), hospices and palliative care networks (no studies). Nine recommendations on CGA-based prognostic tools were issues based on 42 included studies carried out in general practices and primary care (5 studies), medical and surgical clinics (4 studies), and hospital wards (33 studies).

RESULTS

Using CGA can be useful to reduce hospitalization, mortality, institutionalization, the risk of delirium, and improve appropriateness in drug prescription and maintain functional activities in different settings. Further research on the efficacy of CGA in rehabilitative facilities, nursing homes, and hospice and palliative-care settings is recommended. CGA-based tools, particularly the Multidimensional Prognostic Index, should be used to predict some negative outcomes in different settings.

CONCLUSIONS

This Guideline may be useful in clinical practice and as a tool to support research on the use of CGA in older people.

摘要

背景

该指南由意大利全科医生-初级保健和老年医学医院-社区协会推广,并在国家卫生研究所和一个专家小组的参与下进行,该小组包括来自 25 个科学和卫生专业组织的代表。该指南的目的是制定基于证据的建议,评估 CGA 在不同临床环境下对老年人的疗效,以及基于 CGA 的工具评估预后的准确性和实用性。

方法

根据意大利国家指南系统和 NICE 标准(英国国家卫生与保健卓越研究所)的方法手册,该指南是基于推荐评估、制定和评价的分级方法制定的。通过数据库搜索初步筛选出超过 20000 条记录。根据符合纳入标准并在全科诊所和初级保健机构(26 项研究)、内科和外科诊所(16 项研究)、急诊部门(17 项研究)、医院内科和外科病房(53 项研究)、长期护理设施和疗养院(5 项研究)、临终关怀机构和姑息治疗网络(无研究)进行的 117 项研究,确定了 16 项关于 CGA 疗效的建议。基于在全科诊所和初级保健机构(5 项研究)、内科和外科诊所(4 项研究)以及医院病房(33 项研究)进行的 42 项纳入研究,确定了 9 项关于基于 CGA 的预后工具的建议。

结果

在不同的环境中使用 CGA 可以减少住院、死亡率、住院、谵妄风险,并改善药物处方的适当性,维持功能活动。建议进一步研究 CGA 在康复设施、疗养院、临终关怀和姑息治疗环境中的疗效。建议在不同环境中使用基于 CGA 的工具,特别是多维预后指数,来预测一些负面结果。

结论

本指南在临床实践中可能有用,也可以作为支持老年人使用 CGA 研究的工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ced/11128394/d5b725100df1/40520_2024_2772_Fig1_HTML.jpg

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