Dicle University Science and Technology Application and Research Center, 21280, Diyarbakır, Turkey; Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Dicle University, 21280, Diyarbakir, Turkey.
Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Dicle University, 21280, Diyarbakir, Turkey.
Chemosphere. 2024 Jul;360:142387. doi: 10.1016/j.chemosphere.2024.142387. Epub 2024 May 25.
This study was designed to investigate the toxic effects of two frequently used commercial insecticides containing endosulfan and indoxacarb on a freshwater amphipod Gammarus kischineffensis. In this context, the 24, 48, 72 and 96 h LC50 values of these pesticides were determined for G. kischineffensis. Then the histopathological effects of these pesticides on the gill tissues of this species were evaluated. At the end of the study, the 96 h LC50 values of commercial-grade endosulfan and indoxacarb for G. kischineffensis were determined as 1.861 μg L and 20.212 mg L, respectively. Histopathologically, the most common histopathological alterations in individuals exposed to sublethal concentrations of commercial-grade endosulfan and indoxacarb were pillar cell hypertrophy resulting in atrophy of the hemocoelic space and hemocytic infiltration. Considering these results, it can be said that commercial-grade endosulfan is extremely and indoxacarb is slightly toxic to G. kischineffensis.
本研究旨在探讨两种常用的含硫丹和茚虫威的商业杀虫剂对淡水端足目甲壳动物克氏原螯虾的毒性作用。在此背景下，测定了这两种农药对克氏原螯虾的 24、48、72 和 96 h LC50 值。然后，评估了这些杀虫剂对该物种鳃组织的组织病理学影响。研究结束时，确定商业级硫丹和茚虫威对克氏原螯虾的 96 h LC50 值分别为 1.861 μg/L 和 20.212 mg/L。组织病理学检查结果表明，暴露于商业级硫丹和茚虫威亚致死浓度下的个体最常见的组织病理学改变是柱形细胞肥大，导致血腔空间萎缩和血细胞浸润。考虑到这些结果，可以说商业级硫丹对克氏原螯虾具有极高毒性，而茚虫威具有轻微毒性。
