Ma Lan-Lan, Chen Ling, Wang Qin, Xu Yang-Guang, Chen Xing
Department of Pediatric Respiratory Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2024 May 15;26(5):476-480. doi: 10.7499/j.issn.1008-8830.2311149.
To investigate the control status of bronchial asthma (referred to as "asthma") in school-age children with normal pulmonary ventilation function and the occurrence of acute attacks within 1 year of follow-up.
A retrospective analysis was conducted on clinical data of 327 children aged 6-14 years with bronchial asthma and normal pulmonary ventilation function from April to September 2021. Based on the measured value of one second rate (FEV/FVC), the children were divided into the ≥80% group (267 cases) and the <80% group (60 cases). The pulmonary ventilation function, asthma control level, and occurrence of acute attacks within 1 year were compared between the two groups.
The baseline pulmonary ventilation function in the <80% group was lower than that in the ≥80% group, and the proportion of small airway dysfunction was higher than that in the ≥80% group (<0.05). After standardized treatment for 1 year, the small airway function indices in the <80% group improved but remained lower than those in the ≥80% group (<0.05). The rate of incomplete asthma control at baseline was 34.6% (113/327), and the asthma control level in the <80% group was lower than that in the ≥80% group (<0.05). After standardized treatment for 1 year, the asthma control level in the <80% group remained lower than that in the ≥80% group, and the proportion of acute asthma attacks was higher than that in the ≥80% group (<0.05).
Approximately one-third of school-age children with asthma still have incomplete asthma control when their pulmonary ventilation function is normal. Among them, children with measured FEV/FVC<80% have an increased risk of acute asthma attacks and require close follow-up and strengthened asthma management.
探讨肺通气功能正常的学龄期儿童支气管哮喘（简称“哮喘”）的控制状况及随访1年内急性发作情况。
对2021年4月至9月327例6~14岁肺通气功能正常的支气管哮喘患儿临床资料进行回顾性分析。根据一秒率（FEV/FVC）测定值，将患儿分为≥80%组（267例）和<80%组（60例）。比较两组肺通气功能、哮喘控制水平及随访1年内急性发作情况。
<80%组基线肺通气功能低于≥80%组，小气道功能障碍比例高于≥80%组（P<0.05）。标准化治疗1年后，<80%组小气道功能指标有所改善，但仍低于≥80%组（P<0.05）。基线时哮喘控制不佳率为34.6%（113/327），<80%组哮喘控制水平低于≥80%组（P<0.05）。标准化治疗1年后，<80%组哮喘控制水平仍低于≥80%组，急性哮喘发作比例高于≥80%组（P<0.05）。
约三分之一肺通气功能正常的学龄期哮喘患儿哮喘控制不佳。其中，FEV/FVC测定值<80%的患儿急性哮喘发作风险增加，需密切随访并加强哮喘管理。
