Arruda M S, Arruda O S, Astolfi C S, Opromolla D V
Hospital Lauro de Souza Lima.
Hansenol Int. 1985;10(1-2):23-31.
Hanseniasis patients and contacts of Virchowian patients, totaling 467 persons have been submitted to Mitsuda's reaction. These individuals have been divided into five groups: group 1 compounded of 59 persons, relatives of Virchowian patients; group 2 - 171 persons, employees of the Hospital Lauro de Souza Lima working there for more than one year; group 3 - 127 hanseniasis patients in activity, Mitsuda negative; group 4 - 63 hanseniasis patients in activity, Mitsuda positive; group 5 - 47 Virchowian patients, inactive, Mitsuda negative. The analysis of the data showed that: a) hanseniasis patients, both Mitsuda positive and negative, do not present positivity to Fernandez's reaction; b) early reaction can be observed more frequently in individuals of group 1 than in those of group 2. Mitsuda's antigen causes the reversal of Fernandez's reaction in about 30% of indirect contacts; c) the percentage of negative Mitsuda's reactions (without induration) does not differ between groups 1 and 2, though indurations smaller than 5 mm have been as many as 10 times more frequent in individuals of group 1. A second application of the antigen in Mitsuda negative persons showed the reversal of the test in 100% of the tested subjects.
467名麻风病患者及类麻风患者的接触者接受了光田反应检测。这些个体被分为五组：第一组由59名类麻风患者的亲属组成；第二组有171人，是在劳罗·德索萨·利马医院工作一年以上的员工；第三组是127名现症麻风病患者，光田反应阴性；第四组是63名现症麻风病患者，光田反应阳性；第五组是47名非现症类麻风患者，光田反应阴性。数据分析表明：a）光田反应阳性和阴性的麻风病患者对费尔南德斯反应均无阳性表现；b）第一组个体比第二组个体更频繁地观察到早期反应。光田抗原在约30%的间接接触者中导致费尔南德斯反应逆转；c）第一组和第二组光田反应阴性（无硬结）的百分比没有差异，尽管第一组个体中小于5毫米的硬结出现频率多达10倍。对光田反应阴性者再次应用抗原，结果显示100%的受试对象检测结果逆转。
