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基于多源信息融合的白术多维质量属性一致性评价

[Consistency evaluation of multidimensional quality attributes of Atractylodis Macrocephalae Rhizoma by fusion of multi-source information].

作者信息

Han Yan-Yu, Wu Zhi-Sheng, Dai Ping, Wang Kai-Yi, Zhao Jing, Zhang Xiao-Meng, Wang Xiao-Meng, Wang Jing, Huan Xing-Yue, Guo Xin-Yu, Li Nan, Yao Lu, Wang Shu-Ying, Wang Yi-Fei

机构信息

School of Chinese Materia Medica,Beijing University of Chinese Medicine Beijing 102488,China Engineering Research Center for Pharmaceutics of Chinese Materia Medica and New Drug Development,Ministry of Education Beijing 102488,China.

School of Chinese Materia Medica,Beijing University of Chinese Medicine Beijing 102488,China Engineering Research Center for Pharmaceutics of Chinese Materia Medica and New Drug Development,Ministry of Education Beijing 102488,China School of Pharmacy,Fujian University of Traditional Chinese Medicine Fuzhou 350122,China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2024 May;49(9):2434-2440. doi: 10.19540/j.cnki.cjcmm.20240111.302.

Abstract

The quality control of Chinese medicinal decoction pieces is one of the key tasks in the traditional Chinese medicine industry. In this study, multi-source information fusion was employed to fuse the data from near-infrared spectroscopy, electronic tongues, and other tests and establish an overall quality consistency evaluation method for Atractylodis Macrocephalae Rhizoma, which provided methodological support for the overall quality evaluation of Atractylodis Macrocephalae Rhizoma. The near-infrared spectroscopy information was measured in both static and dynamic states for 23 batches of Atractylodis Macrocephalae Rhizoma samples from different sources, and the electronic tongue sensory information, moisture content, and leachate content were measured. The overall quality of Atractylodis Macrocephalae Rhizoma was evaluated by multi-source information fusion. The results showed that the near-infrared spectroscopy information of 16122103, 801000509, 801000352, 701003656, HX21L01, and 160956 was different from that of other batches of Atractylodis Macrocephalae Rhizoma powder in the static state, and 701003298, 16122103, 701003656, 701003107, 801000229, and 18090404 were the different batches in the dynamic state. The moisture content showed no significant difference between batches. The leachate content in the batch 801000509 was different from that in other batches. The electronic tongue sensory information of 150721004, 151237, 160703004, HX21M01, HX21K04, HX21K01, and 601003516 was different from that of other batches. Furthermore, data layer fusion was employed to analyze the overall quality of Atractylodis Macrocephalae Rhizoma. Four batches, 150721004, HX21M01, HX21K04, and HX21K01, showed the parameters exceeding the 95% control limits and differed from the other samples in terms of the overall quality. This study integrated the information of moisture, near-infrared spectroscopy, and other sources to evaluate the quality consistency among 23 batches of Atractylodis Macrocephalae Rhizoma samples, which provides a reference for the quality consistency evaluation of Chinese medicinal decoction pieces.

摘要

中药饮片的质量控制是中药行业的关键任务之一。本研究采用多源信息融合方法,融合近红外光谱、电子舌等检测数据,建立了白术整体质量一致性评价方法,为白术整体质量评价提供了方法学支持。对23批不同来源的白术样品进行了近红外光谱信息的静态和动态测定,并测定了电子舌感官信息、水分含量和浸出物含量。通过多源信息融合对白术的整体质量进行评价。结果表明,16122103、801000509、801000352、701003656、HX21L01和160956的近红外光谱信息在静态下与其他批次白术粉不同,701003298、16122103、701003656、701003107、801000229和18090404在动态下为不同批次。批次间水分含量无显著差异。801000509批次的浸出物含量与其他批次不同。150721004、151237、160703004、HX21M01、HX21K04、HX21K01和601003516的电子舌感官信息与其他批次不同。此外,采用数据层融合分析白术的整体质量。150721004、HX21M01、HX21K04和HX21K01这4个批次的参数超过了95%的控制限,整体质量与其他样品不同。本研究综合水分、近红外光谱等多源信息,对23批白术样品的质量一致性进行评价,为中药饮片质量一致性评价提供参考。

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