Division of Pulmonary, Critical Care & Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Northwell, New Hyde Park, New York, USA.
Respirology. 2024 Jul;29(7):563-573. doi: 10.1111/resp.14764. Epub 2024 May 29.
Malignant Central Airway Obstruction (MCAO) encompasses significant and symptomatic narrowing of the central airways that can occur due to primary lung cancer or metastatic disease. Therapeutic bronchoscopy is associated with high technical success and symptomatic relief and includes a wide range of airway interventions including airway stents. Published literature suggests that stenting practices vary significantly across the world primarily due to lack of guidance. This document aims to address this knowledge gap by addressing relevant questions related to airway stenting in MCAO. An international group of 17 experts from 17 institutions across 11 countries with experience in using airway stenting for MCAO was convened as part of this guideline statement through the World Association for Bronchology and Interventional Pulmonology (WABIP). We performed a literature and internet search for reports addressing six clinically relevant questions. This guideline statement, consisting of recommendations addressing these six PICO questions, was formulated by a systematic and rigorous process involving the evaluation of published evidence, augmented with expert experience when necessary. Panel members participated in the development of the final recommendations using the modified Delphi technique.
恶性中央气道阻塞(MCAO)包括主要由原发性肺癌或转移性疾病引起的中央气道显著且有症状的狭窄。治疗性支气管镜检查与较高的技术成功率和症状缓解相关,包括广泛的气道干预措施,包括气道支架。已发表的文献表明,支架置入术的实践在全球范围内存在显著差异,主要是由于缺乏指导。本文件旨在通过解决与 MCAO 气道支架置入相关的相关问题来解决这一知识空白。通过世界支气管镜和介入肺科协会(WABIP),召集了来自 11 个国家的 17 个机构的 17 名具有 MCAO 气道支架置入经验的专家组成了一个国际专家组。我们对涉及六个临床相关问题的报告进行了文献和互联网搜索。该指南声明由涉及这六个 PICO 问题的建议组成,是通过评估已发表的证据并在必要时结合专家经验,经过系统和严格的过程制定的。小组成员使用修改后的 Delphi 技术参与了最终建议的制定。