Division of Allergy and Clinical Immunology, Department of Chest Diseases, Faculty of Medicine, Hacettepe University, Ankara, Turkiye.
Division of Immunology and Allergic Diseases Ankara City Hospital, Faculty of Medicine, Ankara Yıldırım Beyazıt University, Ankara, Turkiye.
Turk J Med Sci. 2023 Nov 18;54(1):309-315. doi: 10.55730/1300-0144.5792. eCollection 2024.
BACKGROUND/AIM: Characteristics of asthma in the elderly population is not well-known. The aim of the present study was to evaluate asthma in the elderly population, to compare disease characteristics between patients diagnosed <60 (aged asthma) and ≥60 (elderly asthma) years of age.
The study was a prospective, multicenter, cross-sectional type. A questionnaire was filled out to patients 60 years of age and over, that have been followed for asthma for at least 3 months. Asthma Control Test (ACT), eight-item Morisky Medication Adherence Scale (MMAS-8) was filled out, inhaler device technique was assessed.
A total of 399 patients were included from 17 tertiary care centers across the country. Mean age was 67.11 years and 331 (83%) were female. The age at asthma diagnosis was ≥60 in 146 (36.6%) patients. Patients diagnosed ≥60 years were older (p < 0.001), had higher education level (p < 0.001), more commonly had first-degree relative with asthma (p = 0.038), asthma related comorbidities (p = 0.009) and accompanying rhinitis/rhinosinusitis (p = 0.005), had better asthma control (p = 0.001), were using less controller medications (p = 0.014). Inhaler technique was correct in 37% of the patients with no difference in between the groups. Treatment compliance was better in elderly asthma patients (p < 0.001). In the multivariate logistic regression analysis, having well-controlled asthma (odds ratio = 1.61, CI = 1.04-2.51), and high medication adherence rate (odds ratio = 2.43, CI = 1.48-4.0) were associated with being in the elderly asthma group.
The characteristics of asthma are different among patients aged 60 years and over which seems to be related to onset age of asthma. In our cohort, the elderly asthma patients had higher education level, and treatment adherence and asthma control was better. Patients diagnosed ≥60 years of age did not have more severe disease.
背景/目的：老年人哮喘的特征尚不清楚。本研究旨在评估老年人群中的哮喘，并比较<60 岁（年轻哮喘）和≥60 岁（老年哮喘）患者之间的疾病特征。
本研究为前瞻性、多中心、横断面研究。对至少 3 个月确诊为哮喘的 60 岁及以上患者进行问卷调查。填写哮喘控制测试（ACT）、八项Morisky 药物依从性量表（MMAS-8），评估吸入器装置技术。
共纳入来自全国 17 个三级保健中心的 399 名患者。平均年龄为 67.11 岁，331 名（83%）为女性。哮喘诊断年龄≥60 岁的患者为 146 名（36.6%）。诊断年龄≥60 岁的患者年龄较大（p<0.001），受教育程度较高（p<0.001），一级亲属中哮喘患者更为常见（p=0.038），与哮喘相关的合并症（p=0.009）和伴随的鼻炎/鼻窦炎（p=0.005），哮喘控制更好（p=0.001），使用的控制药物较少（p=0.014）。37%的患者吸入器技术正确，两组之间无差异。老年哮喘患者的治疗依从性更好（p<0.001）。多变量逻辑回归分析显示，哮喘控制良好（比值比=1.61，95%置信区间=1.04-2.51）和高药物依从率（比值比=2.43，95%置信区间=1.48-4.0）与老年哮喘组相关。
60 岁及以上患者的哮喘特征不同，这似乎与哮喘的发病年龄有关。在我们的队列中，老年哮喘患者的受教育程度较高，治疗依从性和哮喘控制更好。诊断年龄≥60 岁的患者病情并不更严重。
