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环境协变量的特征工程改进了基于植物基因组的预测。

Feature engineering of environmental covariates improves plant genomic-enabled prediction.

作者信息

Montesinos-López Osval A, Crespo-Herrera Leonardo, Pierre Carolina Saint, Cano-Paez Bernabe, Huerta-Prado Gloria Isabel, Mosqueda-González Brandon Alejandro, Ramos-Pulido Sofia, Gerard Guillermo, Alnowibet Khalid, Fritsche-Neto Roberto, Montesinos-López Abelardo, Crossa José

机构信息

Facultad de Telemática, Universidad de Colima, Colima, Mexico.

International Maize and Wheat Improvement Center (CIMMYT), Texcoco, Edo. de Mexico, Mexico.

出版信息

Front Plant Sci. 2024 May 15;15:1349569. doi: 10.3389/fpls.2024.1349569. eCollection 2024.

DOI:10.3389/fpls.2024.1349569
PMID:38812738
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11135473/
Abstract

INTRODUCTION

Because Genomic selection (GS) is a predictive methodology, it needs to guarantee high-prediction accuracies for practical implementations. However, since many factors affect the prediction performance of this methodology, its practical implementation still needs to be improved in many breeding programs. For this reason, many strategies have been explored to improve the prediction performance of this methodology.

METHODS

When environmental covariates are incorporated as inputs in the genomic prediction models, this information only sometimes helps increase prediction performance. For this reason, this investigation explores the use of feature engineering on the environmental covariates to enhance the prediction performance of genomic prediction models.

RESULTS AND DISCUSSION

We found that across data sets, feature engineering helps reduce prediction error regarding only the inclusion of the environmental covariates without feature engineering by 761.625% across predictors. These results are very promising regarding the potential of feature engineering to enhance prediction accuracy. However, since a significant gain in prediction accuracy was observed in only some data sets, further research is required to guarantee a robust feature engineering strategy to incorporate the environmental covariates.

摘要

引言

由于基因组选择(GS)是一种预测方法,在实际应用中需要保证较高的预测准确性。然而,由于许多因素会影响该方法的预测性能,在许多育种计划中,其实际应用仍需改进。因此,人们探索了许多策略来提高该方法的预测性能。

方法

当将环境协变量作为基因组预测模型的输入时,此信息有时仅有助于提高预测性能。因此,本研究探索对环境协变量进行特征工程处理,以提高基因组预测模型的预测性能。

结果与讨论

我们发现,在各个数据集中,通过特征工程处理,与未进行特征工程处理仅纳入环境协变量相比,预测误差在所有预测变量上平均降低了761.625%。这些结果对于特征工程提高预测准确性的潜力而言非常有前景。然而,由于仅在部分数据集中观察到预测准确性有显著提高,因此需要进一步研究以确保有一个稳健的特征工程策略来纳入环境协变量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f43d/11135473/9cd6f4078a15/fpls-15-1349569-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f43d/11135473/e65f577ae092/fpls-15-1349569-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f43d/11135473/19d79a688571/fpls-15-1349569-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f43d/11135473/9cd6f4078a15/fpls-15-1349569-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f43d/11135473/e65f577ae092/fpls-15-1349569-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f43d/11135473/19d79a688571/fpls-15-1349569-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f43d/11135473/9cd6f4078a15/fpls-15-1349569-g003.jpg

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本文引用的文献

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2
Genomic versus phenotypic selection to improve corn borer resistance and grain yield in maize.通过基因组选择与表型选择提高玉米对玉米螟的抗性和籽粒产量
Front Plant Sci. 2023 Jul 7;14:1162440. doi: 10.3389/fpls.2023.1162440. eCollection 2023.
3
DNNGP, a deep neural network-based method for genomic prediction using multi-omics data in plants.
利用整合次要性状和环境协变量的多核基因组预测模型提高小麦关键生物量分配性状的预测准确性。
Plant Genome. 2025 Jun;18(2):e70052. doi: 10.1002/tpg2.70052.
DNNGP,一种基于深度神经网络的方法,用于利用植物中的多组学数据进行基因组预测。
Mol Plant. 2023 Jan 2;16(1):279-293. doi: 10.1016/j.molp.2022.11.004. Epub 2022 Nov 10.
4
Empirical comparison of genomic and phenotypic selection for resistance to Fusarium ear rot and fumonisin contamination in maize.玉米对镰刀菌穗腐病和伏马毒素污染抗性的基因组选择和表型选择的实证比较
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Improvement of prediction ability by integrating multi-omic datasets in barley.在大麦中整合多组学数据集以提高预测能力。
BMC Genomics. 2022 Mar 12;23(1):200. doi: 10.1186/s12864-022-08337-7.
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