Liu Baoshan, Li Muyuan, Wang Jian, Zhang Fengli, Wang Fangze, Jin Caicai, Li Jiayi, Wang Yanran, Sanderson Thomas Hudson, Zhang Rui
School of Clinical Medicine, Shandong Second Medical University, Weifang People's Hospital, Weifang, China.
Department of Cardiology, Key Laboratory of Cardiopulmonary-Cerebral Resuscitation Research of Weifang, The First Affiliated Hospital of Shandong Second Medical University, Weifang People's Hospital, Weifang, China.
Front Nutr. 2024 May 15;11:1387268. doi: 10.3389/fnut.2024.1387268. eCollection 2024.
Cardiac arrest is a leading cause of death globally. Only 25.8% of in-hospital and 33.5% of out-of-hospital individuals who achieve spontaneous circulation following cardiac arrest survive to leave the hospital. Respiratory failure and acute coronary syndrome are the two most common etiologies of cardiac arrest. Effort has been made to improve the outcomes of individuals resuscitated from cardiac arrest. Magnesium is an ion that is critical to the function of all cells and organs. It is often overlooked in everyday clinical practice. At present, there have only been a small number of reviews discussing the role of magnesium in cardiac arrest. In this review, for the first time, we provide a comprehensive overview of magnesium research in cardiac arrest focusing on the effects of magnesium on the occurrence and prognosis of cardiac arrest, as well as in the two main diseases causing cardiac arrest, respiratory failure and acute coronary syndrome. The current findings support the view that magnesium disorder is associated with increased risk of cardiac arrest as well as respiratory failure and acute coronary syndrome.
心脏骤停是全球主要的死亡原因之一。心脏骤停后实现自主循环的住院患者中只有25.8%存活出院，院外患者的这一比例为33.5%。呼吸衰竭和急性冠状动脉综合征是心脏骤停最常见的两种病因。人们一直在努力改善心脏骤停复苏患者的预后。镁是一种对所有细胞和器官功能至关重要的离子，在日常临床实践中常常被忽视。目前，仅有少数综述讨论了镁在心脏骤停中的作用。在本综述中，我们首次全面概述了心脏骤停中镁的研究情况，重点关注镁对心脏骤停的发生和预后的影响，以及在导致心脏骤停的两种主要疾病——呼吸衰竭和急性冠状动脉综合征中的作用。目前的研究结果支持这样一种观点，即镁紊乱与心脏骤停、呼吸衰竭和急性冠状动脉综合征风险增加有关。
