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非综合征性单侧唇腭裂患者行与不行修复手术时鼻唇变化的纵向研究

A Longitudinal Investigation of Nasolabial Changes With and Without Revision Surgery in Patients with Non-Syndromic Unilateral Cleft Lip and Palate.

作者信息

Dabbagh Wasna, Groff Destin, Stauffer Lexi, Newland Mary, Lo Alexis, Hiller Andrea, Long Ross E

机构信息

Lancaster Cleft Palate Clinic, Hershey, PA, USA.

Pennsylvania State University College of Medicine, Hershey, PA, USA.

出版信息

Cleft Palate Craniofac J. 2025 Aug;62(8):1376-1384. doi: 10.1177/10556656241256706. Epub 2024 May 30.

DOI:10.1177/10556656241256706
PMID:38813767
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12198462/
Abstract

ObjectiveTo determine a baseline of anticipated change in nasolabial appearance following primary repair of unilateral cleft lip/palate and evaluate the degree to which revision surgery improves nasolabial appearance.DesignRetrospective chart review.SettingPatients treated at the Lancaster Cleft Palate Clinic interdisciplinary clinic.PatientsTwenty-three patients with complete unilateral cleft lip and palate who underwent primary surgical repair and 19 additional patients who underwent subsequent revision surgery were included.InterventionsPatients in the non-revision group underwent a Tennison-Randall triangular flap lip repair at 3mo. Patients in the revision group underwent a modification of the Nakajima straight-line repair after primary Tennison-Randall triangular flap lip repair at an average age of 141mo.Main Outcome MeasuresA modification of the Asher-McDade Aesthetic Index was utilized to evaluate Nasolabial Frontal (NLF), Nasolabial Profile (NLP), Vermillion Border (VB), and total change in appearance. Scores for patients in the revision group were evaluated before and after revision while appearance for patients without revision was evaluated at 3 distinct ages. Scores were averaged across time-points and inter-rater reliability was assessed.ResultsNasolabial appearance in the non-revision sample did not change significantly over time, except for nasal profile. Scores improved after revision surgery - NLP: 3.48 to 2.97, (p = 0.001); NLF: 3.50 to 2.95 (p = 0.001); and Total Nasolabial Score: 3.29 to 3.01 (p = 0.004), with no significant change in VB.ConclusionDecisions regarding need for nasolabial revision surgery may be made as early as 5yo with successful outcomes following secondary surgery improving appearance except for vermillion border appearance.

摘要

目的

确定单侧唇腭裂一期修复术后鼻唇外观预期变化的基线,并评估修复手术改善鼻唇外观的程度。

设计

回顾性图表审查。

地点

在兰开斯特腭裂诊所多学科诊所接受治疗的患者。

患者

纳入23例接受一期手术修复的完全性单侧唇腭裂患者以及另外19例接受后续修复手术的患者。

干预措施

未进行修复组的患者在3个月时接受坦尼森-兰德尔三角瓣唇修复术。修复组的患者在平均年龄141个月时,在一期坦尼森-兰德尔三角瓣唇修复术后接受中岛直线修复术改良。

主要观察指标

采用改良的阿舍-麦克戴德美学指数评估鼻唇正面(NLF)、鼻唇侧面(NLP)、唇红缘(VB)及外观的总体变化。对修复组患者在修复前后进行评分评估,而对未进行修复的患者在3个不同年龄阶段评估其外观。对各时间点的评分进行平均,并评估评分者间信度。

结果

除鼻侧面外,未进行修复样本的鼻唇外观随时间未发生显著变化。修复手术后评分有所改善——NLP:从3.48降至2.97,(p = 0.001);NLF:从3.50降至2.95(p = 0.001);鼻唇总评分:从3.29降至3.01(p = 0.004),唇红缘无显著变化。

结论

关于鼻唇修复手术需求的决策最早可在5岁时做出,二期手术后外观改善效果良好,但唇红缘外观除外。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8f9/12198462/c7dcb81def89/10.1177_10556656241256706-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8f9/12198462/066380af1681/10.1177_10556656241256706-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8f9/12198462/c3bd3ac3ccf3/10.1177_10556656241256706-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8f9/12198462/c8b8a2778d63/10.1177_10556656241256706-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8f9/12198462/6e03dcd5dd25/10.1177_10556656241256706-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8f9/12198462/c7dcb81def89/10.1177_10556656241256706-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8f9/12198462/066380af1681/10.1177_10556656241256706-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8f9/12198462/c3bd3ac3ccf3/10.1177_10556656241256706-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8f9/12198462/c8b8a2778d63/10.1177_10556656241256706-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8f9/12198462/6e03dcd5dd25/10.1177_10556656241256706-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8f9/12198462/c7dcb81def89/10.1177_10556656241256706-fig5.jpg

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本文引用的文献

1
The Americleft Project: Comparison of Ratings Using Two-Dimensional Versus Three-Dimensional Images for Evaluation of Nasolabial Appearance in Patients With Unilateral Cleft Lip and Palate.美国腭裂项目:二维与三维图像用于评估单侧唇腭裂患者鼻唇外观的评分比较
J Craniofac Surg. 2018 Jan;29(1):105-108. doi: 10.1097/SCS.0000000000004102.
2
The Americleft Project: A Modification of Asher-McDade Method for Rating Nasolabial Esthetics in Patients With Unilateral Cleft Lip and Palate Using Q-sort.美国腭裂项目:一种对阿舍-麦克戴德法的改良,用于通过Q分类法评估单侧唇腭裂患者的鼻唇美学。
J Craniofac Surg. 2017 Nov;28(8):1911-1917. doi: 10.1097/SCS.0000000000003787.
3
The Americleft Project: Burden of Care from Secondary Surgery.
美国腭裂项目:二次手术的护理负担
Plast Reconstr Surg Glob Open. 2015 Aug 10;3(7):e442. doi: 10.1097/GOX.0000000000000415. eCollection 2015 Jul.
4
The Burden of Care for Children With Unilateral Cleft Lip: A Systematic Review of Revision Surgery.单侧唇裂患儿的护理负担:修复手术的系统评价
Cleft Palate Craniofac J. 2016 Jul;53(4):84-94. doi: 10.1597/14-202. Epub 2015 Aug 6.
5
The Americleft Project: A Proposed Expanded Nasolabial Appearance Yardstick for 5- to 7-Year-Old Patients With Complete Unilateral Cleft Lip and Palate (CUCLP).美国腭裂项目:一项针对5至7岁完全性单侧唇腭裂(CUCLP)患者的拟议扩大鼻唇外观衡量标准。
Cleft Palate Craniofac J. 2016 Jan;53(1):30-7. doi: 10.1597/14-017. Epub 2015 Apr 6.
6
Aesthetic outcome and the need for revision of unilateral cleft lip repair at Komfo Anokye Teaching Hospital.科姆福·阿诺克耶教学医院单侧唇裂修复的美学效果及修复需求
Ghana Med J. 2014 Mar;48(1):20-3. doi: 10.4314/gmj.v48i1.3.
7
Cleft lip and/or palate: review.唇腭裂:综述
Minerva Stomatol. 2014 Apr;63(4):111-26.
8
Interrater reliability: the kappa statistic.组内一致性:kappa 统计量。
Biochem Med (Zagreb). 2012;22(3):276-82.
9
Cleft lip, cleft palate, and velopharyngeal insufficiency.唇裂、腭裂和腭咽闭合不全。
Plast Reconstr Surg. 2011 Oct;128(4):342e-360e. doi: 10.1097/PRS.0b013e3182268e1b.
10
The Americleft study: an inter-center study of treatment outcomes for patients with unilateral cleft lip and palate part 4. Nasolabial aesthetics.美国腭裂研究:一项关于单侧唇腭裂患者治疗效果的多中心研究 第4部分。鼻唇美学。
Cleft Palate Craniofac J. 2011 May;48(3):259-64. doi: 10.1597/09-186.1. Epub 2011 Jan 10.