Department of Philosophy, Linguistics and Theory of Science, University of Gothenburg, Gothenburg, Sweden.
Centre for Antibiotic Resistance Research in Gothenburg (CARe), Gothenburg, Sweden.
Glob Health Action. 2024 Dec 31;17(1):2343318. doi: 10.1080/16549716.2024.2343318. Epub 2024 May 30.
Local and global surveillance of antibiotic resistance (ABR) has proven a challenge to implement effectively in low- and middleincome (LMI) settings. Environmental surveillance solutions are increasingly highlighted as a strategy to help overcome such problems, and thus to promote global health as well as the local management of ABR in LMI countries. While technical and scientific aspects of such solutions are being probed continuously, no study has investigated their practical feasibility.
Explore practical barriers for environmental surveillance of ABR in LMI countries, and pathways for surveillance experts to manage these.
To start charting this unknown territory, we conducted an explorative, qualitative interview study with key informants, applying a constructivist grounded theory approach to analyze the results.
Barriers were identified across infrastructural, institutional and social dimensions, and pathways to manage them were mostly counterproductive from an ABR management perspective, including avoiding entire regions, applying substandard methods and failing to include local collaborators.
The research community as well as international agencies, organizations and states have key roles and responsibilities for improving the prospects of feasible environmental ABR surveillance in LMI-settings.
在中低收入国家（LMIC），对抗生素耐药性（ABR）进行局部和全球监测，已被证明难以有效实施。环境监测解决方案越来越多地被突出为一种策略，以帮助克服这些问题，从而促进全球健康以及 LMIC 国家对 ABR 的本地管理。虽然这些解决方案的技术和科学方面不断得到探索，但尚无研究调查其实用可行性。
探讨 LMIC 国家进行 ABR 环境监测的实际障碍，以及监测专家管理这些障碍的途径。
为了开始探索这片未知领域，我们对主要利益相关者进行了探索性的定性访谈研究，采用建构主义扎根理论方法来分析结果。
障碍存在于基础设施、机构和社会层面，而从 ABR 管理的角度来看，管理这些障碍的途径大多适得其反，包括避开整个地区、使用不合标准的方法和未能纳入当地合作者。
研究界以及国际机构、组织和国家在改善 LMIC 环境中可行的 ABR 监测前景方面具有关键作用和责任。
