Armstrong Matthew, Hume Emily, McNeillie Laura, Chambers Francesca, Wakenshaw Lynsey, Burns Graham, Heslop Marshall Karen, Vogiatzis Ioannis
Department of Rehabilitation and Sport Sciences, Faculty of Health and Social Sciences, Bournemouth University, Poole, UK.
Department of Sport, Exercise and Rehabilitation, School of Health and Life Sciences, Northumbria University, Newcastle, UK.
ERJ Open Res. 2023 Sep 11;9(5). doi: 10.1183/23120541.00074-2023. eCollection 2023 Sep.
Patients with COPD who exhibit elevated levels of anxiety and/or depression are typically less able to improve symptoms and physical activity levels following a programme of pulmonary rehabilitation (PR). The objective of the present study was to provide proof of concept that offering an intervention comprising cognitive behavioural therapy (CBT) alongside physical activity behavioural modification strategies (BPA) during PR is more effective in improving physical activity outcomes compared to PR and CBT alone.
32 patients with COPD (mean±sd forced expiratory volume in 1 s 42±14% predicted) were assigned 1:1 to receive PR+CBT+BPA or PR+CBT. BPA comprised motivational interviews, step-count monitoring, feedback using a pedometer and goal setting. Assessments included accelerometer-derived steps per day, movement intensity, 6-min walk distance (6MWD) and Hospital Anxiety and Depression Scale (HADS) scores.
The magnitude of improvement across physical activity outcomes was greater for the PR+CBT+BPA compared to the PR+CBT intervention (by 829 steps per day (p=0.029) and by 80±39 vector magnitude units (p=0.042), respectively). Compared to PR and CBT alone, the PR+CBT+BPA intervention induced greater clinically meaningful improvements in HADS anxiety scores (by -2 units, 95% CI -4-1 units) and 6MWD (by 33±20 m).
Providing anxious and/or depressed patients with COPD with a combined intervention of CBT and BPA during PR presents more favourable improvements in physical activity outcome measures compared to CBT alone during PR.
慢性阻塞性肺疾病(COPD)患者若表现出焦虑和/或抑郁水平升高,在接受肺康复(PR)计划后通常较难改善症状和身体活动水平。本研究的目的是提供概念验证,即与单独的PR和认知行为疗法(CBT)相比,在PR期间提供包括CBT和身体活动行为改变策略(BPA)的干预措施,在改善身体活动结果方面更有效。
32例COPD患者(1秒用力呼气量平均±标准差为预测值的42±14%)按1:1分配,分别接受PR+CBT+BPA或PR+CBT。BPA包括动机访谈、步数监测、使用计步器反馈和目标设定。评估包括加速度计测量的每日步数、运动强度、6分钟步行距离(6MWD)和医院焦虑抑郁量表(HADS)评分。
与PR+CBT干预相比,PR+CBT+BPA在身体活动结果方面的改善幅度更大(分别为每天多829步(p=0.029)和多80±39向量幅度单位(p=0.042))。与单独的PR和CBT相比,PR+CBT+BPA干预在HADS焦虑评分(降低-2分,95%CI-4至-1分)和6MWD(增加33±20米)方面带来了更具临床意义的改善。
与在PR期间单独进行CBT相比,在PR期间为患有COPD的焦虑和/或抑郁患者提供CBT和BPA的联合干预,在身体活动结果测量方面呈现出更有利的改善。