DANMEL：一个用于分析与细菌耐药性相关的移动遗传元件的人工整理参考数据库。
DANMEL: A manually curated reference database for analyzing mobile genetic elements associated with bacterial drug resistance.
作者信息
Wang Peng, Jiang Xiaoyuan, Mu Kai, Jing Ying, Yin Zhe, Cui Yujun, Li Cuidan, Luo Xinhua, Chen Fangzhou, Yu Ting, Zhu Zhichen, Sun Yansong, Chen Fei, Zhou Dongsheng
机构信息
State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and Epidemiology Beijing China.
Beijing Institute of Genomics, Chinese Academy of Sciences China National Center for Bioinformation Beijing China.
出版信息
mLife. 2022 Dec 11;1(4):460-464. doi: 10.1002/mlf2.12046. eCollection 2022 Dec.
We have developed a manually curated online reference database, DANMEL (http://124.239.252.254/danmel/), that addresses the lack of accurate dissection and annotation of the genetic structures of mobile genetic elements (MGEs) with genes for drug resistance. DANMEL contains accurately annotated and genetically dissected reference MGEs covering 5 categories and 135 subcategories/subfamilies of MGEs. Further, DANMEL provides a detailed guide on how to precisely annotate MGEs. DANMEL also provides SEARCH/BLAST functions to facilitate finding reference MGEs. Overall, DANMEL will aid researchers to conduct in-depth genetic analysis of sequenced bacterial MGEs with drug-resistance genes and further facilitate a better understanding of bacterial MGEs associated with drug resistance at a genomic level.
Zotero 插件