Al-Shakarchi Faiz I
Department of Ophthalmology, College of Medicine, Al-Mustansiriya University, Baghdad, Iraq.
Middle East Afr J Ophthalmol. 2014 Oct-Dec;21(4):291-5. doi: 10.4103/0974-9233.142263.
To determine the etiologies of uveitis and the causes of visual loss in uveitis patients at a referral center in Baghdad, Iraq.
A 4-year prospective study was performed at the uveitis clinic at Ibn Al-Haetham teaching eye hospital in Baghdad, Iraq. Referral cases of active uveitis were included. A complete ophthalmic examination was performed in all cases. If clinical picture did not indicate a specific etiology, patients were sent for a routine set of tests while ancillary tests were conducted when indicated.
Out of 318 patients included in this study, 236 patients (74.2%) had bilateral uveitis, and 212 patients (66.7%) had non-granulomatous uveitis. Posterior uveitis was recorded in 123 cases (38.7%) followed by panuveitis in 97 cases (30.5%), anterior uveitis in 78 cases (24.5%), and intermediate uveitis in 20 cases (6.3%). A diagnosis was established in 210 cases (66%) while etiology could not be determined in the remaining 108 cases (34%). Most common infectious causes were toxoplasmosis (13.8%) and presumed ocular tuberculosis (11.4%) while most common non-infectious causes were Vogt-Koyanagi-Harada disease (12.3%), Behηet's disease (8.2%), and pars planitis (5.7%). Out of 49 eyes with irreversible blindness, macular degenerations, or scars (46.9%) and optic nerve atrophy (34.7%) were the most important causes.
At this referral center, toxoplasmosis and presumed ocular tuberculosis were the most common infectious causes of uveitis while Vogt-Koyanagi-Harada disease, Behηet's disease, and pars planitis were, in that order, the most common non-infectious causes. Macular degenerations or scars and optic nerve atrophy were the most important causes of irreversible blindness.
确定伊拉克巴格达一家转诊中心葡萄膜炎患者的葡萄膜炎病因及视力丧失原因。
在伊拉克巴格达伊本·海赛姆教学眼科医院的葡萄膜炎诊所进行了一项为期4年的前瞻性研究。纳入活动性葡萄膜炎的转诊病例。对所有病例进行了全面的眼科检查。如果临床表现未提示特定病因,则将患者送去进行常规检查,如有指征则进行辅助检查。
本研究纳入的318例患者中,236例(74.2%)患有双侧葡萄膜炎,212例(66.7%)患有非肉芽肿性葡萄膜炎。记录到后葡萄膜炎123例(38.7%),全葡萄膜炎97例(30.5%),前葡萄膜炎78例(24.5%),中间葡萄膜炎20例(6.3%)。210例(66%)确诊,其余108例(34%)病因未明确。最常见的感染性病因是弓形虫病(13.8%)和疑似眼结核(11.4%),最常见的非感染性病因是伏格特-小柳-原田病(12.3%)、白塞病(8.2%)和中间葡萄膜炎(5.7%)。在49只出现不可逆失明、黄斑变性或瘢痕的眼中,黄斑变性或瘢痕(46.9%)和视神经萎缩(34.7%)是最重要的病因。
在该转诊中心,弓形虫病和疑似眼结核是葡萄膜炎最常见的感染性病因,伏格特-小柳-原田病、白塞病和中间葡萄膜炎依次是最常见的非感染性病因。黄斑变性或瘢痕以及视神经萎缩是不可逆失明的最重要病因。