Wetzel R C, Setzer N, Stiff J L, Rogers M C
Anesth Analg. 1985 Feb;64(2):125-8.
Because we have noticed dramatic hemodynamic responses in brain dead patients undergoing surgery for organ donation, we analyzed the anesthetic records of cadaver organ donors. Ten records contain complete data for heart rate, blood pressure, central venous pressure, and time of incision. Systolic pressure increased by a mean of 31 torr (P less than 0.01), diastolic pressure by 16 torr (P less than 0.02), and heart rate by 23 beats/min (P less than 0.01) in response to surgical stimulation. These results demonstrate the occurrence of significant hemodynamic responses to surgical stimuli in patients who fulfill the criteria of brain death, responses that do not, however, invalidate the current criteria for the diagnosis of brain death.
由于我们注意到在接受器官捐献手术的脑死亡患者中出现了显著的血流动力学反应，我们分析了尸体器官捐献者的麻醉记录。十份记录包含了心率、血压、中心静脉压和切口时间的完整数据。对手术刺激的反应是，收缩压平均升高31托（P<0.01），舒张压升高16托（P<0.02），心率升高23次/分钟（P<0.01）。这些结果表明，符合脑死亡标准的患者对手术刺激会出现显著的血流动力学反应，然而，这些反应并不会使当前脑死亡的诊断标准无效。
