Non-Communicable Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran; Department of Internal Medicine, Ali-Ibn Abi-Talib Hospital, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Physiology-Pharmacology Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran; Department of Physiology and Pharmacology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
J Affect Disord. 2024 Sep 15;361:139-145. doi: 10.1016/j.jad.2024.05.157. Epub 2024 May 31.
Depressed people are susceptible to metabolic syndrome ression and metabolic syndrome in the Rafsanjan Youth Cohort Study in 2021.
In this cross-sectional study, the data of 3005 young people aged 15-35 under the coverage of urban and rural health centers was investigated in the enrollment stage of the Rafsanjan Youth Cohort Study as a part of the prospective epidemiological research studies in IrAN (PERSIAN). Data was collected using face-to-face interview and electronic questionnaires of the Rafsanjan Youth Cohort Study.
Age of the youth was 25.78 ± 6.06 years, 56 % (n = 1682) were female. The prevalence of metabolic syndrome (MetS) was 7.7 % (95 % CI: 6.8 %-8.8 %) and the prevalence of depression was 11.1 % (95 % CI: 10.0 %-12.3 %). Depression did not have a significant impact on the odds ratio of developing MetS in young people (P = 0.604). The odds ratio (OR) of MetS increases by 1.057 times with increasing age (95 % CI for OR: 1.020-1.094). This OR is also 1.715 times higher in married young people than in unmarried Youth (95 % CI for OR: 1.715-2.692) and 0.196 times lower in young people with medium and high MET index than in young people with low MET index (95 % CI for OR: 0.048-0.811).
Inability to determine a causal relationship between MetS and depression.
Due to the growing trend of components of MetS among the young population, this issue needs to be addressed in future policies and planning for prevention and control as a health priority.
在 2021 年的拉夫桑詹青年队列研究中，抑郁人群易患代谢综合征。
在这项横断面研究中，作为伊朗前瞻性流行病学研究（PERSIAN）的一部分，在拉夫桑詹青年队列研究的入组阶段，对城乡卫生中心覆盖下的 3005 名 15-35 岁的年轻人进行了调查。数据通过面对面访谈和拉夫桑詹青年队列研究的电子问卷收集。
年轻人的年龄为 25.78 ± 6.06 岁，56%（n=1682）为女性。代谢综合征（MetS）的患病率为 7.7%（95%CI：6.8%-8.8%），抑郁的患病率为 11.1%（95%CI：10.0%-12.3%）。抑郁对年轻人患代谢综合征的比值比（OR）没有显著影响（P=0.604）。随着年龄的增长，MetS 的 OR 增加 1.057 倍（95%CI 为 OR：1.020-1.094）。已婚年轻人的 OR 比未婚年轻人高 1.715 倍（95%CI 为 OR：1.715-2.692），而 MET 指数中、高的年轻人的 OR 比低 MET 指数的年轻人低 0.196 倍（95%CI 为 OR：0.048-0.811）。
无法确定 MetS 和抑郁之间的因果关系。
由于年轻人代谢综合征的组成部分呈增长趋势，因此在未来的政策和规划中，需要将其作为优先健康事项，以预防和控制这一问题。
