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顽固性肿胀:一例表现为腮腺肿胀的木村病罕见病例。

Stubborn Swellings: A Rare Case of Kimura's Disease Presenting as Parotid Swellings.

作者信息

Rai Pranjal, Ankathi Sumankumar, Panchal Nitin, Janu Amit, Yadav Subhash

机构信息

Radiodiagnosis, Tata Memorial Hospital, Homi Bhabha National Institute (HBNI), Mumbai, IND.

Pathology, Tata Memorial Hospital, Homi Bhabha National Institute (HBNI), Mumbai, IND.

出版信息

Cureus. 2024 May 3;16(5):e59570. doi: 10.7759/cureus.59570. eCollection 2024 May.

Abstract

Kimura disease (KD) is a rare chronic inflammatory disorder characterized by the development of painless subcutaneous nodules, predominantly in the head and neck region. Diagnosis relies on a high index of clinical suspicion and clinicopathological correlation, with core biopsy serving as the gold standard for a definitive diagnosis. While the disease itself is benign, it can cause significant morbidity if left untreated. This case report describes a 48-year-old male who presented with bilateral infraauricular swellings, pruritus, and elevated serum IgE levels along with eosinophilia. Imaging and histopathological correlation confirmed the diagnosis of KD. Combination therapy of corticosteroids and cyclosporine resulted in significant clinical improvement, highlighting the efficacy of the approach while avoiding surgical resection. This case emphasizes the importance of radiologic-pathologic correlation along with the use of serology to effectively diagnose KD, even in atypical presentations.

摘要

木村病(KD)是一种罕见的慢性炎症性疾病,其特征是出现无痛性皮下结节,主要位于头颈部区域。诊断依赖于高度的临床怀疑以及临床病理相关性,核心活检是确诊的金标准。虽然该疾病本身是良性的,但如果不治疗可能会导致严重的发病率。本病例报告描述了一名48岁男性,其表现为双侧耳下肿胀、瘙痒、血清IgE水平升高以及嗜酸性粒细胞增多。影像学和组织病理学相关性证实了木村病的诊断。皮质类固醇和环孢素联合治疗导致了显著的临床改善,突出了该方法的有效性,同时避免了手术切除。本病例强调了放射学-病理学相关性以及血清学检测在有效诊断木村病中的重要性,即使在非典型表现中也是如此。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a311/11144294/9b8d8f9eaa58/cureus-0016-00000059570-i01.jpg

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