Kondrashin Anatoly, Rabinovich Susanna, Sergiev Vladimir, Tokmalaev Anatoly
Sechenov First Moscow State Medical University, Moscow, Russia.
Peoples' Friendship University of Russia, Moscow, Russia.
Malariaworld J. 2013 May 2;4:3. doi: 10.5281/zenodo.10894616. eCollection 2013.
An imported case of presumably Chesson strain from Myanmar to Moscow is presented. In the absence of radical treatment with primaquine the patient experienced a series of 5 subsequent relapses after treatment with Delagil (chloroquine). The period between relapses ranged from 47-61 days. It is concluded that importation of Chesson-like strains with high relapse frequencies, in conjunction with their relative tolerance to primaquine and the absence of adequate treatment with this drug, might result in the re-establishment of local transmission in areas free of malaria but with high receptivity.
本文介绍了一例从缅甸输入到莫斯科的疑似切森株疟疾病例。在未使用伯氨喹进行根治治疗的情况下,患者在用氯胍(氯喹)治疗后经历了5次后续复发。复发间隔时间为47 - 61天。结论是,输入复发频率高的切森样菌株,加上它们对伯氨喹相对耐受且缺乏该药物的充分治疗,可能导致在无疟疾但易感性高的地区重新建立本地传播。