Zeng Hong-Ze, Yi Hang, He Song, Wu Rong, Ning Bo
Department of Gastroenterology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Front Med (Lausanne). 2024 May 17;11:1380640. doi: 10.3389/fmed.2024.1380640. eCollection 2024.
The sphincter of Oddi is a delicate neuromuscular structure located at the junction of the biliary-pancreatic system and the duodenum. Sphincter of Oddi Dysfunction (SOD) can result in various clinical manifestations, including biliary-type pain and recurrent idiopathic pancreatitis. The management of SOD has been challenging. With the publication of the landmark Evaluating Predictors and Interventions in Sphincter of Oddi Dysfunction (EPISOD) trial and the Rome IV consensus, our clinical practice in the treatment of SOD has changed significantly in recent years. Currently, the management of type II SOD remains controversial and there is a lack of non-invasive therapy options, particularly for patients not responding to endoscopic treatment. In this mini review, we aimed to discuss the current knowledge on the treatment of biliary SOD.
奥迪括约肌是一个位于胆胰系统与十二指肠交界处的精细神经肌肉结构。奥迪括约肌功能障碍（SOD）可导致多种临床表现，包括胆源性疼痛和复发性特发性胰腺炎。SOD的管理一直具有挑战性。随着具有里程碑意义的“评估奥迪括约肌功能障碍的预测因素和干预措施（EPISOD）试验”以及《罗马IV共识》的发表，近年来我们在SOD治疗方面的临床实践发生了显著变化。目前，II型SOD的管理仍存在争议，并且缺乏非侵入性治疗选择，尤其是对于内镜治疗无反应的患者。在这篇小型综述中，我们旨在讨论目前关于胆源性SOD治疗的知识。
