• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

使用半刚性结构对长节段胸段进行稳定化的封顶操作可能对预防近端交界性后凸具有有利的生物力学效应:一项生物力学比较。

Topping-Off a Long Thoracic Stabilization With Semi-Rigid Constructs May Have Favorable Biomechanical Effects to Prevent Proximal Junctional Kyphosis: A Biomechanical Comparison.

作者信息

Cadieux Chloe, Brzozowski Pawel, Fernandes Renan J R, McGregor Martine E, Zdero Radovan, Bailey Christopher S, McLachlin Stewart D, Rasoulinejad Parham

机构信息

London Health Science Centre Combined Neurosurgical and Orthopaedic Spine Program, Schulich School of Medicine, Western University, London, ON, Canada.

Orthopaedic Biomechanics Lab, Victoria Hospital, London, ON, Canada.

出版信息

Global Spine J. 2025 Apr;15(3):1685-1694. doi: 10.1177/21925682241259695. Epub 2024 Jun 3.

DOI:10.1177/21925682241259695
PMID:38828634
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11571626/
Abstract

Study DesignIn-vitro cadaveric biomechanical study.ObjectivesLong posterior spinal fusion is a standard treatment for adult spinal deformity. However, these rigid constructs are known to alter motion and stress to the adjacent non-instrumented vertebrae, increasing the risk of proximal junctional kyphosis (PJK). This study aimed to biomechanically compare a standard rigid construct vs constructs "topped off" with a semi-rigid construct. By understanding semi-rigid constructs' effect on motion and overall construct stiffness, surgeons and researchers could better optimize fusion constructs to potentially decrease the risk of PJK and the need for revision surgery.MethodsNine human cadaveric spines (T1-T12) underwent non-destructive biomechanical range of motion tests in pure bending or torsion and were instrumented with an all-pedicle-screw (APS) construct from T6-T9. The specimens were sequentially instrumented with semi-rigid constructs at T5: (i) APS plus sublaminar bands; (ii) APS plus supralaminar hooks; (iii) APS plus transverse process hooks; and (iv) APS plus short pedicle screws.ResultsAPS plus transverse process hooks had a range of motion (ie, relative angle) for T4-T5 and T5-T6, as well as an overall mechanical stiffness for T1-T12, that was more favourable, as it reduced motion at adjacent levels without a stark increase in stiffness. Moreover, APS plus transverse process hooks had the most linear change for range of motion across the entire T3-T7 range.ConclusionsPresent findings suggest that APS plus transverse process hooks has a favourable biomechanical effect that may reduce PJK for long spinal fusions compared to the other constructs examined.

摘要

研究设计

体外尸体生物力学研究。

目的

后路长节段脊柱融合术是成人脊柱畸形的标准治疗方法。然而,已知这些刚性内固定结构会改变相邻未植入器械椎体的运动和应力,增加近端交界性后凸(PJK)的风险。本研究旨在对标准刚性内固定结构与采用半刚性结构“封顶”的内固定结构进行生物力学比较。通过了解半刚性结构对运动和整体结构刚度的影响,外科医生和研究人员可以更好地优化融合结构,以潜在降低PJK风险和翻修手术的必要性。

方法

对9具人类尸体脊柱(T1 - T12)进行了纯弯曲或扭转状态下的非破坏性生物力学活动度测试,并在T6 - T9节段植入全椎弓根螺钉(APS)内固定结构。标本依次在T5节段植入半刚性结构:(i)APS加椎板下带;(ii)APS加上椎板钩;(iii)APS加横突钩;(iv)APS加短椎弓根螺钉。

结果

APS加横突钩在T4 - T5和T5 - T6节段的活动度(即相对角度),以及T1 - T12的整体力学刚度方面更具优势,因为它减少了相邻节段的运动,而刚度没有大幅增加。此外,APS加横突钩在整个T3 - T7范围内的活动度变化最为线性。

结论

目前的研究结果表明,与其他研究的结构相比,APS加横突钩具有良好的生物力学效应,可能会降低长节段脊柱融合术的PJK风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e417/11938545/4269e7c1a958/10.1177_21925682241259695-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e417/11938545/e23073ba9a13/10.1177_21925682241259695-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e417/11938545/9e9d7cd5e287/10.1177_21925682241259695-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e417/11938545/0c99846fe33e/10.1177_21925682241259695-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e417/11938545/9c2f516ead64/10.1177_21925682241259695-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e417/11938545/4269e7c1a958/10.1177_21925682241259695-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e417/11938545/e23073ba9a13/10.1177_21925682241259695-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e417/11938545/9e9d7cd5e287/10.1177_21925682241259695-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e417/11938545/0c99846fe33e/10.1177_21925682241259695-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e417/11938545/9c2f516ead64/10.1177_21925682241259695-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e417/11938545/4269e7c1a958/10.1177_21925682241259695-fig5.jpg

相似文献

1
Topping-Off a Long Thoracic Stabilization With Semi-Rigid Constructs May Have Favorable Biomechanical Effects to Prevent Proximal Junctional Kyphosis: A Biomechanical Comparison.使用半刚性结构对长节段胸段进行稳定化的封顶操作可能对预防近端交界性后凸具有有利的生物力学效应:一项生物力学比较。
Global Spine J. 2025 Apr;15(3):1685-1694. doi: 10.1177/21925682241259695. Epub 2024 Jun 3.
2
Instrumentation techniques to prevent proximal junctional kyphosis and proximal junctional failure in adult spinal deformity correction-a systematic review of biomechanical studies.器械技术预防成人脊柱畸形矫正中近端交界性后凸和近端交界性失败:生物力学研究的系统评价。
Spine J. 2021 May;21(5):842-854. doi: 10.1016/j.spinee.2021.01.011. Epub 2021 Jan 19.
3
Biomechanical comparison of semirigid junctional fixation techniques to prevent proximal junctional failure after thoracolumbar adult spinal deformity correction.半刚性连接固定技术预防胸腰椎成人脊柱畸形矫正后近端交界性失败的生物力学比较。
Spine J. 2021 May;21(5):855-864. doi: 10.1016/j.spinee.2021.01.017. Epub 2021 Jan 23.
4
The effect of posterior polyester tethers on the biomechanics of proximal junctional kyphosis: a finite element analysis.后路聚酯束带对近端交界性后凸生物力学的影响:有限元分析
J Neurosurg Spine. 2017 Jan;26(1):125-133. doi: 10.3171/2016.6.SPINE151477. Epub 2016 Sep 9.
5
Biomechanical assessment of proximal junctional semi-rigid fixation in long-segment thoracolumbar constructs.长节段胸腰椎结构中近端交界区半刚性固定的生物力学评估
J Neurosurg Spine. 2018 Nov 2;30(2):184-192. doi: 10.3171/2018.7.SPINE18136. Print 2019 Feb 1.
6
Transverse process hooks at upper instrumented vertebra provide more gradual motion transition than pedicle screws.在上固定节段椎体处,横突钩比椎弓根螺钉能提供更平缓的运动过渡。
Spine (Phila Pa 1976). 2014 Jun 15;39(14):E826-32. doi: 10.1097/BRS.0000000000000367.
7
Biomechanical Analysis of the Proximal Adjacent Segment after Multilevel Instrumentation of the Thoracic Spine: Do Hooks Ease the Transition?胸椎多节段器械固定后近端相邻节段的生物力学分析:钩是否有助于过渡?
Global Spine J. 2016 Jun;6(4):335-43. doi: 10.1055/s-0035-1563611. Epub 2015 Aug 21.
8
Evaluation of Spinous Process Tethering at the Proximal End of Rigid Constructs: In Vitro Range of Motion and Intradiscal Pressure at Instrumented and Adjacent Levels.刚性内固定近端棘突束带的评估:固定节段及相邻节段的体外活动范围和椎间盘内压力
Int J Spine Surg. 2020 Aug;14(4):571-579. doi: 10.14444/7076. Epub 2020 Jul 31.
9
Evaluation of proximal junctional kyphosis in adolescent idiopathic scoliosis following pedicle screw, hook, or hybrid instrumentation.评价青少年特发性脊柱侧凸后路经椎弓根螺钉、钩或混合内固定术后近端交界性后凸。
Spine (Phila Pa 1976). 2010 Jan 15;35(2):177-81. doi: 10.1097/BRS.0b013e3181c77f8c.
10
Biomechanical Evaluation of Semi-rigid Junctional Fixation Using a Novel Cable Anchor System to Prevent Proximal Junctional Failure in Adult Spinal Deformity Surgery.使用新型缆索锚固系统对半刚性节段固定进行生物力学评估,以预防成人脊柱畸形手术中的近端节段失败
Spine (Phila Pa 1976). 2022 May 1;47(9):E415-E422. doi: 10.1097/BRS.0000000000004228. Epub 2021 Sep 24.

引用本文的文献

1
Adjacent Segment Motion of Stand-Alone ALIF Versus TLIF in the Degenerative Spine: A Biomechanical Study.退变性脊柱中单独前路腰椎椎间融合术与经椎间孔腰椎椎间融合术的相邻节段运动:一项生物力学研究
Global Spine J. 2025 May 14:21925682251341823. doi: 10.1177/21925682251341823.

本文引用的文献

1
Biomechanical evaluation of different semi-rigid junctional fixation techniques using finite element analysis.基于有限元分析的不同半刚性连接固定技术的生物力学评估。
Clin Biomech (Bristol). 2023 Aug;108:106071. doi: 10.1016/j.clinbiomech.2023.106071. Epub 2023 Aug 12.
2
Instrumentation Techniques to Prevent Proximal Junctional Kyphosis and Proximal Junctional Failure in Adult Spinal Deformity Correction: A Systematic Review of Clinical Studies.预防成人脊柱畸形矫正中近端交界性后凸和近端交界性失败的器械技术:临床研究的系统评价
Global Spine J. 2022 Jul;12(6):1282-1296. doi: 10.1177/21925682211034500. Epub 2021 Jul 30.
3
Biomechanical comparison of semirigid junctional fixation techniques to prevent proximal junctional failure after thoracolumbar adult spinal deformity correction.
半刚性连接固定技术预防胸腰椎成人脊柱畸形矫正后近端交界性失败的生物力学比较。
Spine J. 2021 May;21(5):855-864. doi: 10.1016/j.spinee.2021.01.017. Epub 2021 Jan 23.
4
Adult Spinal Deformity: Current Concepts and Decision-Making Strategies for Management.成人脊柱畸形:当前概念与管理决策策略
Asian Spine J. 2020 Dec;14(6):886-897. doi: 10.31616/asj.2020.0568. Epub 2020 Dec 2.
5
Evaluation of Spinous Process Tethering at the Proximal End of Rigid Constructs: In Vitro Range of Motion and Intradiscal Pressure at Instrumented and Adjacent Levels.刚性内固定近端棘突束带的评估:固定节段及相邻节段的体外活动范围和椎间盘内压力
Int J Spine Surg. 2020 Aug;14(4):571-579. doi: 10.14444/7076. Epub 2020 Jul 31.
6
Adult spinal deformity.成人脊柱畸形。
Lancet. 2019 Jul 13;394(10193):160-172. doi: 10.1016/S0140-6736(19)31125-0. Epub 2019 Jul 11.
7
Proximal junctional failure prevention in adult spinal deformity surgery utilizing interlaminar fixation constructs.在成人脊柱畸形手术中使用椎板间固定结构预防近端交界性失败
Orthop Rev (Pavia). 2019 May 23;11(2):8068. doi: 10.4081/or.2019.8068.
8
Incidence of Acute, Progressive, and Delayed Proximal Junctional Kyphosis Over an 8-Year Period in Adult Spinal Deformity Patients.8 年内成人脊柱畸形患者急性、进展性和迟发性近端交界性后凸的发生率。
Oper Neurosurg (Hagerstown). 2020 Jan 1;18(1):75-82. doi: 10.1093/ons/opz128.
9
Paraspinal muscle size as an independent risk factor for proximal junctional kyphosis in patients undergoing thoracolumbar fusion.脊柱旁肌肉大小是胸腰椎融合术后近端交界性后凸的独立危险因素。
J Neurosurg Spine. 2019 May 31;31(3):380-388. doi: 10.3171/2019.3.SPINE19108. Print 2019 Sep 1.
10
Treatment of adult thoracolumbar spinal deformity: past, present, and future.成人胸腰椎脊柱畸形的治疗:过去、现在和未来。
J Neurosurg Spine. 2019 May 1;30(5):551-567. doi: 10.3171/2019.1.SPINE181494.