Cadieux Chloe, Brzozowski Pawel, Fernandes Renan J R, McGregor Martine E, Zdero Radovan, Bailey Christopher S, McLachlin Stewart D, Rasoulinejad Parham
London Health Science Centre Combined Neurosurgical and Orthopaedic Spine Program, Schulich School of Medicine, Western University, London, ON, Canada.
Orthopaedic Biomechanics Lab, Victoria Hospital, London, ON, Canada.
Global Spine J. 2025 Apr;15(3):1685-1694. doi: 10.1177/21925682241259695. Epub 2024 Jun 3.
Study DesignIn-vitro cadaveric biomechanical study.ObjectivesLong posterior spinal fusion is a standard treatment for adult spinal deformity. However, these rigid constructs are known to alter motion and stress to the adjacent non-instrumented vertebrae, increasing the risk of proximal junctional kyphosis (PJK). This study aimed to biomechanically compare a standard rigid construct vs constructs "topped off" with a semi-rigid construct. By understanding semi-rigid constructs' effect on motion and overall construct stiffness, surgeons and researchers could better optimize fusion constructs to potentially decrease the risk of PJK and the need for revision surgery.MethodsNine human cadaveric spines (T1-T12) underwent non-destructive biomechanical range of motion tests in pure bending or torsion and were instrumented with an all-pedicle-screw (APS) construct from T6-T9. The specimens were sequentially instrumented with semi-rigid constructs at T5: (i) APS plus sublaminar bands; (ii) APS plus supralaminar hooks; (iii) APS plus transverse process hooks; and (iv) APS plus short pedicle screws.ResultsAPS plus transverse process hooks had a range of motion (ie, relative angle) for T4-T5 and T5-T6, as well as an overall mechanical stiffness for T1-T12, that was more favourable, as it reduced motion at adjacent levels without a stark increase in stiffness. Moreover, APS plus transverse process hooks had the most linear change for range of motion across the entire T3-T7 range.ConclusionsPresent findings suggest that APS plus transverse process hooks has a favourable biomechanical effect that may reduce PJK for long spinal fusions compared to the other constructs examined.
研究设计
体外尸体生物力学研究。
目的
后路长节段脊柱融合术是成人脊柱畸形的标准治疗方法。然而,已知这些刚性内固定结构会改变相邻未植入器械椎体的运动和应力,增加近端交界性后凸(PJK)的风险。本研究旨在对标准刚性内固定结构与采用半刚性结构“封顶”的内固定结构进行生物力学比较。通过了解半刚性结构对运动和整体结构刚度的影响,外科医生和研究人员可以更好地优化融合结构,以潜在降低PJK风险和翻修手术的必要性。
方法
对9具人类尸体脊柱(T1 - T12)进行了纯弯曲或扭转状态下的非破坏性生物力学活动度测试,并在T6 - T9节段植入全椎弓根螺钉(APS)内固定结构。标本依次在T5节段植入半刚性结构:(i)APS加椎板下带;(ii)APS加上椎板钩;(iii)APS加横突钩;(iv)APS加短椎弓根螺钉。
结果
APS加横突钩在T4 - T5和T5 - T6节段的活动度(即相对角度),以及T1 - T12的整体力学刚度方面更具优势,因为它减少了相邻节段的运动,而刚度没有大幅增加。此外,APS加横突钩在整个T3 - T7范围内的活动度变化最为线性。
结论
目前的研究结果表明,与其他研究的结构相比,APS加横突钩具有良好的生物力学效应,可能会降低长节段脊柱融合术的PJK风险。