Department of Medicine, University of Virginia, Charlottesville, Virginia.
icddr,b, Mohakhali, Dhaka, Bangladesh.
Am J Trop Med Hyg. 2024 Jun 4;111(1):3-4. doi: 10.4269/ajtmh.24-0012. Print 2024 Jul 3.
Malnutrition in children, defined as a child who is more than 2 standard deviations below the norm for height- or weight-for-age, is a pervasive, population-wide problem in low- and middle-income countries. Malnutrition is associated with increased infant mortality and delayed neurocognitive development. A recent pooled analysis of more than 30 longitudinal cohort studies demonstrated that the conditions mothers lived in during pregnancy, and their access to adequate nutrition, was a major factor in the subsequent growth and health of their children. We review here this analysis and the hypothesis that interventions to address childhood malnutrition need to start before birth and continue throughout the critical first 1,000 days of life.
儿童营养不良是指身高或体重与年龄相比低于两个标准差的儿童,这是中低收入国家普遍存在的、涉及整个人口的问题。营养不良与婴儿死亡率增加和神经认知发育迟缓有关。最近对 30 多项纵向队列研究的汇总分析表明,母亲在怀孕期间的生活条件及其获得充足营养的机会是其子女后续生长和健康的主要因素。我们在此回顾了这一分析以及以下假设:解决儿童营养不良问题的干预措施需要在出生前开始,并持续到生命的最初 1000 天。