病例报告：原发性卵巢癌腋窝淋巴结转移：两例报告及文献复习

Case report: Axillary lymph node metastases from primary ovarian cancer: a report of two cases and literature review.

作者信息

Abdullah Norlia, Rosly Nadiah, Pauzi Suria Hayati Md, Mustapha Aida Widure, Arifuddin Yulianty

机构信息

Department of Surgery, Medical Faculty, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.

Department of Surgery, Ipoh General Hospital, Ipoh, Perak, Malaysia.

出版信息

Front Oncol. 2024 May 21;14:1384306. doi: 10.3389/fonc.2024.1384306. eCollection 2024.

DOI:10.3389/fonc.2024.1384306

PMID:38835392

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11148327/

Abstract

Ovarian cancer is usually confined intraperitoneally. Distant metastases at presentation is unusual. Its spread via lymphatics is uncommon, and metastasis to axillary lymph nodes is very rare. We report two cases with presentation of axillary lymphadenopathy without breast involvement. Computed tomography scan identified the ovarian masses. Both had elevated Serum Ca 125. The first case had a Grade 2 ovarian endometrioid carcinoma. The second case had a high-grade serous ovarian carcinoma. These cases illustrate the rarity of axillary lymphadenopathy from ovarian cancer. It is important to identify the primary ovarian carcinoma in order to offer appropriate management. Despite surgery and chemotherapy, both succumbed within 3 years from diagnosis.

摘要

卵巢癌通常局限于腹腔内。初诊时出现远处转移并不常见。其通过淋巴管扩散并不常见，转移至腋窝淋巴结则极为罕见。我们报告两例表现为腋窝淋巴结肿大且无乳腺受累的病例。计算机断层扫描发现了卵巢肿块。两例患者的血清Ca 125均升高。第一例为2级卵巢子宫内膜样癌。第二例为高级别浆液性卵巢癌。这些病例说明了卵巢癌导致腋窝淋巴结肿大的罕见性。识别原发性卵巢癌以提供恰当的治疗很重要。尽管接受了手术和化疗，两人均在确诊后3年内死亡。