Amy Maya, Roberts Sanford E, Arisi Maria F, Collingwood Robin, Maguire Lillias
Surgery, Drexel University College of Medicine, Philadelphia, USA.
Surgery, University of Pennsylvania, Philadelphia, USA.
Cureus. 2024 May 5;16(5):e59660. doi: 10.7759/cureus.59660. eCollection 2024 May.
Mucinous cystic neoplasms (MCNs) are rare tumors primarily observed in the pancreas but occasionally found in other locations such as the retroperitoneum, ovary, liver, and spleen. These neoplasms are histologically classified based on the degree of dysplasia, with some associated with invasive carcinoma. Colorectal surgeons infrequently encounter MCNs. Mesenteric MCNs pose a diagnostic challenge secondary to their atypical location, subtle histology, and lack of specific biochemical markers. In this context, we present a case involving a 68-year-old female who initially presented with an assumed ovarian mass. Subsequent exploration revealed a 12 cm MCN situated in the sigmoid mesentery, a location seldom associated with these tumors. The patient underwent laparotomy with successful resection and recovery. Histopathological analysis confirmed the neoplasm's mucinous epithelium with a complex papillary architecture. Immunohistochemical staining supported the diagnosis, revealing positivity for CK7, SATB2, and CDX2.
黏液性囊性肿瘤(MCNs)是一种罕见的肿瘤,主要见于胰腺,但偶尔也见于其他部位,如腹膜后、卵巢、肝脏和脾脏。这些肿瘤根据发育异常程度进行组织学分类,有些与浸润性癌有关。结直肠外科医生很少遇到MCNs。肠系膜MCNs因其非典型位置、细微的组织学表现以及缺乏特异性生化标志物而带来诊断挑战。在此背景下,我们报告一例68岁女性病例,该患者最初表现为疑似卵巢肿块。后续探查发现一个12厘米的MCN位于乙状结肠系膜,这是一个很少与这些肿瘤相关的位置。患者接受了剖腹手术,成功切除肿瘤并康复。组织病理学分析证实肿瘤为黏液上皮,具有复杂的乳头状结构。免疫组化染色支持诊断,显示CK7、SATB2和CDX2呈阳性。