Black H S, Castrow F F, Gerguis J
Arch Dermatol. 1985 Mar;121(3):348-9.
A sample of dinitrochlorobenzene, determined by gas-liquid chromatography and mass spectrometry to be greater than 98% pure, was tested in the Salmonella typhimurium plate assay. The chemical evoked a marked mutagenic response at all concentrations tested (3 to 150 micrograms per plate). These results confute the suitability of this agent for the treatment of benign skin disorders.
通过气液色谱法和质谱分析法测定纯度大于98%的二硝基氯苯样品,在鼠伤寒沙门氏菌平板试验中进行了测试。该化学物质在所有测试浓度(每平板3至150微克)下均引发了明显的诱变反应。这些结果证明该药剂不适用于治疗良性皮肤疾病。