Doubleday C W, Wilkin J K
J Am Acad Dermatol. 1982 Mar;6(3):325-7. doi: 10.1016/s0190-9622(82)70023-4.
Dinitrochlorobenzene (DNCB) has been purported to possess potential mutagenic and carcinogenic hazards. This potential hazard may be due to contamination of DNCB with known carcinogenic precursors, mononitrochlorobenzenes. Three samples of commercially available DNCB were analyzed for the presence of such mononitrochlorobenzenes, which were absent in all samples tested. The implications of product contamination with mutagenic and/or carcinogenic impurities may be important for both in vitro Ames microbial assays and potential carcinogenic exposure in human therapy.
二硝基氯苯（DNCB）据称具有潜在的诱变和致癌危害。这种潜在危害可能是由于DNCB被已知的致癌前体一硝基氯苯污染所致。对三个市售DNCB样品进行了分析，检测其中此类一硝基氯苯的存在情况，结果在所测试的所有样品中均未发现。产品被诱变和/或致癌杂质污染的影响，对于体外艾姆斯微生物试验和人类治疗中的潜在致癌暴露可能都很重要。
