Schmidt W, Hendrik H
Geburtshilfe Frauenheilkd. 1985 Feb;45(2):91-7. doi: 10.1055/s-2008-1036212.
Results of sonographic determination of the length of femur between the 12th and 42nd week of pregnancy are presented. The length of femoral diaphysis was determined as part of a cross-sectional study on a total of 595 patients who were not at risk, and where the gestation age was known and confirmed. The growth function of the foetal femoral length was determined via a polynomic regression equation. The foetal femoral length growth presents a characteristic appearance between the 12th and 42nd pregnancy week. In the 12th pregnancy week it is 11 mm on the average, 33 m in the 20th, 58 mm in the 30th, and 76 mm at birth. After an almost linear progression up to about the 30th week of pregnancy, the growth curve gradually begins to flatten out from that time. The mean growth rate of foetal femoral length during the entire period under observation is about 1 to 3 mm per pregnancy week. The authors present a table showing the 95% interval for estimating the gestational age. A relatively accurate estimate of the gestational age is particularly possible in the "early" range between 5 and 32 mm (corresponding to the 12th to 20th week of pregnancy), namely, +/- 9.7 to 10.3 days (95% interval). In femoral measurement results 33 mm to 76 mm (corresponding to the 20th to 42nd week of pregnancy), the range of error of the estimate is +/- 20.6 days. Additional measurement of the foetal femoral length is useful for on-target diagnosis of malformations, for estimating the gestational age, for growth control/weight estimation, and, in certain cases, also for diagnosing the maturity.
本文展示了妊娠12至42周期间超声测定股骨长度的结果。在一项针对595名无风险孕妇的横断面研究中,测定了股骨干长度,这些孕妇的孕周已知且经确认。通过多项式回归方程确定胎儿股骨长度的生长函数。胎儿股骨长度在妊娠12至42周期间呈现出特征性变化。妊娠12周时平均为11毫米,20周时为33毫米,30周时为58毫米,出生时为76毫米。在妊娠约30周前几乎呈线性增长,此后生长曲线逐渐趋于平缓。在整个观察期内,胎儿股骨长度的平均生长速率约为每周1至3毫米。作者给出了一个表格,显示了用于估计孕周的95%区间。在5至32毫米(相当于妊娠12至20周)的“早期”范围内,尤其有可能相对准确地估计孕周,即误差范围为±9.7至10.3天(95%区间)。对于股骨测量结果在33毫米至76毫米(相当于妊娠20至42周)之间,估计的误差范围为±20.6天。额外测量胎儿股骨长度有助于畸形的靶向诊断、孕周估计、生长监测/体重估计,在某些情况下,还可用于诊断成熟度。