Usmani Wania, de Courten Maximilian, Hanna Fahad
Department of Health, Torrens University Australia, Melbourne, VIC, Australia.
Health and Education Policy, Mitchell Institute, Victoria University, Melbourne, VIC, Australia.
Front Oral Health. 2024 May 22;5:1364765. doi: 10.3389/froh.2024.1364765. eCollection 2024.
Cardiovascular diseases (CVDs) are a significant cause of morbidity and mortality worldwide, resulting in a high socioeconomic burden. Growing evidence has shown a link between oral diseases and several chronic conditions including CVDs. The focus of this review is to investigate and summaries the evidence surrounding oral health interventions and their potential impact on reducing both the risk and/or severity of CVDs.
A scoping review was conducted to examine oral health interventions for managing CVD outcomes and risks. The review adhered to the Joanna Briggs Institute (JBI) framework for evidence synthesis and followed the reporting standards outlined by the Preferred Reporting Items for Systematic Reviews and Meta-analysis- extension to Scoping Review (PRISMA-ScR). A systematic search across EBSCOhost, PubMed, and Scopus databases from 2012 to 2024 was utilized to identify relevant studies. Inclusion criteria focused on English language articles with a sample size of at least 50, evaluating the impact of oral health interventions on CVD outcomes.
Out of the initial 2,154 studies identified in the search, 12 studies met the inclusion and exclusion criteria and were included in the final analysis. Overall, the studies revealed that along with surgical and non-surgical periodontal therapy, regular oral hygiene care practices, including toothbrushing, tongue brushing, and flossing, significantly reduced the risk of cardiovascular events and mortality. These interventions in patients with or without CVD baseline have shown a decrease in CVD risk markers as well as a reduction in bacterial colonization. Similarly, consistent oral hygiene routines, combined with regular dental visits, were associated with a lower risk of heart failure and CVD risk mortality.
The evidence extracted from this review suggests that periodontal therapy, regular dental cleaning, and re-enforcing of oral health regimes can stabilize oral health conditions and subsequently improve CVD progression/risks. However, limited to no evidence exists regarding the therapeutic effects of oral health promotion in managing CVD markers and its direct impact on disease outcomes, warranting further investigation.
心血管疾病(CVDs)是全球发病和死亡的重要原因,造成了高昂的社会经济负担。越来越多的证据表明口腔疾病与包括心血管疾病在内的多种慢性疾病之间存在联系。本综述的重点是调查和总结围绕口腔健康干预措施及其对降低心血管疾病风险和/或严重程度的潜在影响的证据。
进行了一项范围综述,以检查用于管理心血管疾病结局和风险的口腔健康干预措施。该综述遵循乔安娜·布里格斯研究所(JBI)的证据综合框架,并遵循系统评价和Meta分析扩展至范围综述的首选报告项目(PRISMA-ScR)概述的报告标准。利用2012年至2024年在EBSCOhost、PubMed和Scopus数据库中进行的系统检索来识别相关研究。纳入标准侧重于样本量至少为50的英文文章,评估口腔健康干预措施对心血管疾病结局的影响。
在检索中最初识别出的2154项研究中,有12项研究符合纳入和排除标准,并被纳入最终分析。总体而言,研究表明,除了手术和非手术牙周治疗外,定期的口腔卫生护理措施,包括刷牙、刷舌和使用牙线,可显著降低心血管事件和死亡风险。这些干预措施在有或无心血管疾病基线的患者中均显示出心血管疾病风险标志物的降低以及细菌定植的减少。同样,持续的口腔卫生习惯与定期看牙医相结合,与较低的心力衰竭风险和心血管疾病死亡风险相关。
本综述提取的证据表明,牙周治疗、定期牙齿清洁和强化口腔健康方案可以稳定口腔健康状况,进而改善心血管疾病的进展/风险。然而,关于口腔健康促进在管理心血管疾病标志物方面的治疗效果及其对疾病结局的直接影响,几乎没有证据,需要进一步研究。