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探索纳米纤维素在推动制药和生物医学领域变革中的作用。

Exploring nanocellulose's role in revolutionizing the pharmaceutical and biomedical fields.

机构信息

Department of Chemical Engineering, National Institute of Technology Durgapur, Durgapur, West Bengal 713209, India.

Department of Chemical Engineering, National Institute of Technology Durgapur, Durgapur, West Bengal 713209, India.

出版信息

Int J Biol Macromol. 2024 Jun;272(Pt 2):132837. doi: 10.1016/j.ijbiomac.2024.132837. Epub 2024 Jun 6.

DOI:10.1016/j.ijbiomac.2024.132837
PMID:38848844
Abstract

The increasing global demand for eco-friendly products derived from natural resources has spurred intensive research into biomaterials. Among these materials, nanocellulose stands out as a highly efficient option, consisting of tightly packed cellulose fibrils derived from lignocellulosic biomass. Nanocellulose boasts a remarkable combination of attributes, including a high specific surface area, impressive mechanical strength, abundant hydroxyl groups for easy modification, as well as non-toxic, biodegradable, and environmentally friendly properties. Consequently, nanocellulose has been extensively studied for advanced applications. This paper provides a comprehensive overview of the various sources of nanocellulose derived from diverse natural sources and outlines the wide array of production methods available. Furthermore, it delves into the extensive utility of nanocellulose within the biomedical and pharmaceutical industries, shedding light on its potential role in these fields. Additionally, it highlights the significance of nanocellulose composites and their applications, while also addressing key challenges that must be overcome to enable widespread utilization of nanocellulose.

摘要

随着全球对源自自然资源的环保型产品的需求不断增长,人们对生物材料的研究也日益深入。在这些材料中,纳米纤维素作为一种高效的选择脱颖而出,它由木质纤维素生物质中提取的紧密堆积的纤维素原纤维组成。纳米纤维素具有一系列显著的特性,包括高比表面积、令人印象深刻的机械强度、丰富的羟基基团便于进行修饰以及无毒、可生物降解和环保等特性。因此,纳米纤维素已被广泛研究用于先进的应用。本文全面概述了源自不同天然来源的纳米纤维素的各种来源,并概述了现有的广泛的生产方法。此外,本文还深入探讨了纳米纤维素在生物医学和制药行业的广泛应用,阐明了其在这些领域的潜在作用。此外,还强调了纳米纤维素复合材料及其应用的重要性,同时还解决了为实现纳米纤维素的广泛应用必须克服的关键挑战。

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